Results 81 to 90 of about 818,500 (292)

Textile-based wearable sensors for assisting sports performance [PDF]

open access: yes, 2009
There is a need for wearable sensors to assess physiological signals and body kinematics during exercise. Such sensors need to be straightforward to use, and ideally the complete system integrated fully within a garment.
Coyle, Shirley   +4 more
core   +1 more source

Integrative physiology: facts and theories [PDF]

open access: yesEuropean Journal of Applied Physiology, 2008
Nine years ago, upon accepting Dr. Rolf Lange’s invitation, on behalf of Springer-Verlag, to become Editor-in-Chief of the European Journal of Applied Physiology, I was pondering the role of integrative and system physiology in the vast landscape of the life sciences. In spite of the scornful deWnition of “paleophysiology” by some younger colleagues, I
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Towards Integration of Biological and Physiological Functions at Multiple Levels

open access: yesFrontiers in Physiology, 2010
An aim of systems physiology today can be stated as to establish logical and quantitative bridges between phenomenological attributes of physiological entities such as cells and organs and physical attributes of biological entities, i.e., biological ...
Taishin eNomura
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Integration of physiological mechanisms that influence fertility in dairy cows*

open access: yesAnimal, 2008
Fertility in dairy cows has been declining for the past three decades. Genetic selection for increased milk production has been associated with changes in key metabolic hormones (growth hormone, insulin, IGF and leptin) that regulate metabolism by ...
P.C. Garnsworthy, K.D. Sinclair, R. Webb
doaj   +1 more source

Integration of psychological models in the design of artificial creatures [PDF]

open access: yes, 2004
Artificial creatures form an increasingly important component of interactive computer games. Examples of such creatures exist which can interact with each other and the game player and learn from their experiences.
Bryant, Catherine M.   +2 more
core  

Who approves/pays for additional monitoring? [PDF]

open access: yes, 2019
Major considerations in the provision of healthcare are availability, affordability, accessibility, and appropriateness, especially in the setting of heart failure where disease burden is growing, developments have been rapid and newer biomarkers ...
Adamson   +46 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Geographic and habitat origin influence biomass production and storage translocation in the clonal plant Aegopodium podagraria.

open access: yesPLoS ONE, 2014
Through physiological integration, clonal plants can support ramets in unfavourable patches, exploit heterogeneously distributed resources and distribute resources that are taken up over large areas.
Tina D'Hertefeldt   +2 more
doaj   +1 more source

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