Results 101 to 110 of about 818,500 (292)

Enhancing prediction of human traits and behaviors through ensemble learning of traditional and novel resting-state fMRI connectivity analyses

NeuroImage
Recent advances in cognitive neuroscience have focused on using resting-state functional connectivity (RSFC) data from fMRI scans to more accurately predict human traits and behaviors. Traditional approaches generally analyze RSFC by correlating averaged
Takaaki Yoshimoto, Kai Tokunaga, Junichi Chikazoe   +2 more
doaj   +1 more source

Morphological Plasticity and Gas Exchange of Ligustrum lucidumW.T. Aiton in Distinct Light Conditions

Brazilian Archives of Biology and Technology, 2015
The objective of this study was to understand the different morpho-physiological strategies of Ligustrum lucidum, an invasive species occurring in Brazilian forest fragments under heterogeneous light conditions. Ten individuals of L.
Letícia Larcher, Guilherme Nogueira, Maria Regina Boeger   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Modulation of emotional appraisal by false physiological feedback during fMRI [PDF]

, 2004
BACKGROUND James and Lange proposed that emotions are the perception of physiological reactions. Two-level theories of emotion extend this model to suggest that cognitive interpretations of physiological changes shape self-reported emotions ...
Marcus A. Gray, Neil A. Harrison, Stefan Wiens, Hugo D. Critchley, Sheng He, JA Russell, S Wiens, W James, C Lange, S Schachter, B Parkinson, S Valins, S Misovich, SE Taylor, EH Liebhart, JC Barefoot, PC Misovich S Charis, ASR Parkinson B Manstead, CS Carver, SR Truax, KW Kerber, JR Cantor, D Zillman, RM Stern, D Goldstein, EW Thornton, ES Katkin, HD Critchley, HD Critchley, O Pollatos, AD Craig, AD Craig, HD Critchley, HD Critchley, AD Craig, HD Critchley, HD Critchley, R Rosenthal, GP Crucian, MP Paulus, AR Damasio, RD Lane, EM Reiman, DA Fitzgerald, ML Phillips, M Kano, J Feinstein, CB Saper, A Damasio, P Shaw, B Corden, R Adolphs, PJ Whalen, JS Morris, A Puce, JS Winston, G Yovel, HL Gallagher, D Lundqvist, R Deichmann, J Ashburner, KJ Friston, TT Liu, WD Penny, RN Henson   +64 more
core   +5 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix, Grothe, Benedikt, Meyer, Elisabeth M. M., Porres, Christian P.   +3 more
core   +1 more source

Integrated Physiology Extreme Environment

Defence Life Science Journal, 2023
A successful military operation not only necessitates cutting-edge, contemporary weapon systems but also, fittest men behind these machines. These men, desirably with the highest order of physiological and psychological well-being to operate in the harshest of battle fields shape the battle field dynamics through grit and valour.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An Integrated Analysis of the Physiological Effects of Space Flight: Executive Summary [PDF]

A large array of models were applied in a unified manner to solve problems in space flight physiology. Mathematical simulation was used as an alternative way of looking at physiological systems and maximizing the yield from previous space flight ...
Leonard, J. I.
core   +1 more source