Results 71 to 80 of about 1,856,828 (312)

Melatonin: A Potential Shield against Electromagnetic Waves [PDF]

open access: yes, 2022
Melatonin, a vital hormone synthesized by the pineal gland, has been implicated in various physiological functions and circadian rhythm regulation. Its role in the protection against the non-ionizing electromagnetic field (EMF), known to disrupt the body’
Jammoul, Maya   +2 more
core   +1 more source

The physiological significance and potential clinical applications of ghrelin [PDF]

open access: yesEuropean Journal of Internal Medicine, 2012
Ghrelin, a natural ligand for the growth hormone (GH)-secretagogue receptor (GHS-R), is now known to play a role in a number of different physiological processes. For example, ghrelin increases GH secretion, feeding, and body weight when administered centrally or peripherally.
Akamizu, Takashi, Kangawa, Kenji
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Potential physiological correlates of the model parameters.

open access: yes, 2014
Potential physiological correlates of the model parameters.
Selver Demic (646341)   +1 more
core   +1 more source

Transient Receptor Potential Vanilloid (TRPV) channels: Basal Properties and physiological potential [PDF]

open access: yes, 2022
Transient receptor potential vanilloid (TRPV) channels are TRP homologs and have been classified into six subfamilies. They are unique mediators of sensory signals with multiple physiological effects and are potential targets for developing new therapies
Sasase, Tomohiko   +2 more
core   +1 more source

Vigor de sementes de coentro (Coriandrum sativum L.) provenientes de sistemas orgânico e convencional Evaluation of force of coriander (Coriandrum sativum L.) seeds from the organic and conventional systems

open access: yesRevista Brasileira de Plantas Medicinais, 2012
O coentro (Coriandrum sativum L.) é uma hortaliça amplamente consumida no Brasil como condimento. É muito importante, especialmente para a horticultura do Norte e Nordeste do Brasil.
M.A.D. Silva   +2 more
doaj   +1 more source

Physiological quality of Physalis ixocarpa Brot. ex Hornem seeds in relation to maturation stage and growing season

open access: yesPesquisa Agropecuária Tropical, 2023
Physalis ixocarpa is an edible fruit with great economic importance in many countries. The use of high-quality seeds is essential for the success of the crop, so their harvest should be carried out at their maximum point of physiological maturity.
Natália dos Santos Barroso   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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