Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
This study aimed to evaluate the effects of specific LED light spectra on the growth and physiology of Changchuan No. 3 Capsicum annuum L. seedlings. The experimental design involved exposing pepper seedlings to six different spectral light combinations ...
Wanli Zhu +10 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Morphological, physiological, and molecular mechanisms underlying heat stress memory in plants
Increasing climatic unpredictability makes plants suffer different environmental stresses, with escalating global temperatures positioning heat stress as a principal abiotic constraint.
Yi Liu +8 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Physiological response to feeding in little penguins
Physiological response to feeding in little ...
JA Green (14463885) +3 more
core
An investigation into the use of infrared thermography as a tool to assess the physiological stress response in the horse [PDF]
The experiments reported in this thesis investigated the use of temperature measurement using infrared thermography (IRT) as an objective, non-invasive method to identify the physiological stress response in the horse.
Yarnell, K
core
Background: The beet moth, Scrobipalpa ocellatella Boyd, 1858 (Lep.: Gelechiidae), is an increasingly important pest whose climate-driven expansion threatens sugar beet (Beta vulgaris L.) production in Europe.
Ildikó Jócsák +6 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The effect of aromatherapy with breast milk on changes in physiological indicators caused by pentavalent vaccine injection in infants: A clinical trial study [PDF]
Background: Vaccination in infants is a life-saving intervention; however, it can lead to changes in physiological parameters. Therefore, the use of safe methods to modulate these changes is essential.
Haniea Goodarzi +5 more
doaj

