Results 81 to 90 of about 7,637,456 (312)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Psycho-physiological response in an automatic parachute jump

, 2017
Parachute jump is an extreme activity that elicits an intense stress response that affects jumpers' body systems being able to put them at risk. The present research analysed modifications in blood oxygen saturation (BOS), heart rate (HR), cortisol ...
Clemente Suárez, Vicente Javier, Fernández Lucas, Jesús, Clemente-Suárez, Vicente Javier, Robles Pérez, José Juan   +3 more
core   +1 more source

Evaluation of physiological and morphological basis for drought resistance in maize and sorghum [PDF]

, 2004
Includes bibliographical references (leaves 145-171).Drought stress is often the most limiting factor to maize and sorghum production in the semi-arid areas.
Takele, Abuhay
core   +1 more source

Connecticut State Emergency Response Commission [web site] [Harvested on 2014: Jul. 30]

, 2014
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Physiological and Multi-Omics Insights into Drought Adaptation of Poacynum hendersonii Seedlings Under Different Water Deficit Regimes

Agronomy
This study used Poacynum hendersonii (Hook. f.) Woods. seedlings as experimental material. A soil drought group (gradual soil drying) and a PEG-simulated drought group (15% PEG-6000 treatment) were established.
Yongqian Jia, Ya Ding, Qian Wu, Yuehua Yu, Zhiyi Cheng, Zhongwei Wang, Hao Ma   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

SA regulates seed germination and growth in a dose-dependent manner in Nicotiana alata under salt stress

上海师范大学学报. 自然科学版
Using the modified Nicotiana alata as the test material, the seed germination and plant germination of Nicotiana alata under different concentration gradient exogenous salicylic acid (SA) treatments under 150 mmol·L-1 NaCl stress were studied.
ZHANG Ren, MING Jianlin, LIU Pengcheng, MING Feng   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Connecticut State Emergency Response Commission [web site] [Harvested on 2013: Aug. 12]

, 2013
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core   +1 more source