Results 41 to 50 of about 7,996,985 (259)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Heat Wave Adaptations: Unraveling the Competitive Dynamics Between Invasive Wedelia trilobata and Native Wedelia chinensis

Plants
Heat waves (HW) are projected to become more frequent and intense with climate change, potentially enhancing the invasiveness of certain plant species.
Haochen Yu, Cheng Han, Guangqian Ren, Xuanwen Wu, Shanshan Qi, Bin Yang, Miaomiao Cui, Xue Fan, Zhaoqi Zhu, Zhicong Dai, Daolin Du   +10 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Membrane adhesion junctions regulate airway smooth muscle phenotype and function

, 2023
The local environment surrounding airway smooth muscle (ASM) cells has profound effects on the physiological and phenotypic properties of ASM tissues.
Zhang, Wenwu, Wu, Yidi, Gunst, Susan J., Yidi Wu, Susan Gunst, Wenwu Zhang, J. Gunst, Susan   +6 more
core   +1 more source

Assessment of Physiological Responses During Field Science Task Performance: Feasibility and Future Needs

Frontiers in Physiology, 2022
ObjectiveBy understanding the physiological demands of different types of tasks that will be performed during extravehicular activity (EVA) on Mars, human performance safety risks can be mitigated.
Jordan R. Hill, Barrett S. Caldwell
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Suppression of the physiological stress response is not stress

, 2023
International audienceWe must differentiate between stressful and harsh environments to understand animals’ resilience to global change. Harshness is not stress.
Lindelani Makuya, Makuya, Lindelani, Rimbach, Rebecca, Carsten Schradin, Rebecca Rimbach, Neville Pillay, Schradin, Carsten, Pillay, Neville   +7 more
core   +1 more source

Effects of heavy ion mutation induction breeding on growth and physiological characteristics of broccoli

Fushe yanjiu yu fushe gongyi xuebao
Brassica oleracea is one of the important vegetable crops in China. Its seeds are primarily imported. Hence, developing innovative varieties belonging to China is an urgent requirement.
WANG Man, LIU Xiao, DU Yan, KANG Guisen, DING Jianing, LONG Jing, WANG Yuanmeng, YANG Mingjun, ZHOU Libin   +8 more
doaj   +1 more source

German volume training for health promotion: Acute vasopressor, pulmonary and metabolic responses

Frontiers in Physiology, 2022
Resistance training (RT) is increasingly recommended for incorporation into comprehensive fitness or “exercise as medicine” programs. However, the acute effects of RT, and especially its different sub-types, and how they impact health outcomes are not ...
Brandon S. Shaw, Rohan Lloyd, Monica Da Silva, Donne Coetzee, Jason Moran, Sally P. W. Waterworth, Musa L. Mathunjwa, Ina Shaw   +7 more
doaj   +1 more source