Results 51 to 60 of about 7,637,456 (312)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Physiological response to aerosol propellants. [PDF]
Environmental Health Perspectives, 1978 Acute exposures to isobutane, propane, F-12, and F-11 in concentrations of 250, 500, or 1000 ppm for periods of 1 min to 8 hr did not produce any untoward physiological effects as determined by the methods employed which included serial EKG's and continuous monitoring of modified V5 by telemetry during exposure.
R D, Stewart +5 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A model of heart rate kinetics in response to exercise [PDF]
, 2008 We present a mathematical model, in the form of two coupled ordinary differential equations, for the heart rate kinetics in response to exercise. Our heart rate model is an adaptation of the model of oxygen uptake kinetics of Stirling: a physiological ...
Stirling, James +3 more
core
, 2014 Activation of the immune system to clear pathogens and mitigate infection is a costly process that might incur fitness costs. When vertebrates are exposed to pathogens, their first line of defense is the acute-phase response (APR), which consists of a ...
Nord, Andreas, +4 more
core +1 more source
Fushe yanjiu yu fushe gongyi xuebaoBrassica oleracea is one of the important vegetable crops in China. Its seeds are primarily imported. Hence, developing innovative varieties belonging to China is an urgent requirement.
WANG Man +8 more
doaj +1 more source
German volume training for health promotion: Acute vasopressor, pulmonary and metabolic responses
Frontiers in Physiology, 2022 Resistance training (RT) is increasingly recommended for incorporation into comprehensive fitness or “exercise as medicine” programs. However, the acute effects of RT, and especially its different sub-types, and how they impact health outcomes are not ...
Brandon S. Shaw +7 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Leaf Functional Traits of Invasive Grasses Conferring High-Cadmium Adaptation Over Natives
Frontiers in Plant Science, 2022 Heavy metal (HM) contamination resulting from industrialization and urbanization during the Anthropocene along with plant invasion can severely threaten the growth and adaptation of local flora.
Muhammad Ilyas +18 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source