Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Macaque cardiac physiology is sensitive to the valence of passively viewed sensory stimuli. [PDF]
Autonomic nervous system activity is an important component of affective experience. We demonstrate in the rhesus monkey that both the sympathetic and parasympathetic branches of the autonomic nervous system respond differentially to the affective ...
Amaral, David G +2 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Remote assistance for highly automated vehicles (HAVs), i.e., third-party assistance from support staff outside the vehicle in times of the need for assistance, presents a solution to extend the capabilities of HAVs by integrating a third party for ...
Fabian Walocha +3 more
doaj +1 more source
Outcomes following oesophagectomy in patients with oesophageal cancer: a secondary analysis of the ICNARC Case Mix Programme Database [PDF]
Introduction: This report describes the case mix and outcomes of patients with oesophageal cancer admitted to adult critical care units following elective oesophageal surgery in England, Wales and Northern Ireland.
Alderson, Derek +8 more
core +4 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Innovative Drug Delivery Systems for Management of Menopausal Symptoms: A Systematic Review
Zahra Bostani Khalesi,1 Mahmood Abedinzade,2 Mostafa Golshekan2,3 1Department of Midwifery, Biomedicine Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran; 2Department of Physiology, biomedicine research center, trauma ...
Bostani Khalesi Z +2 more
doaj
Editorial: The art of teaching physiology: its place in the integrated curriculum
Amberly Reynolds, Irina Nizamutdinova
doaj +1 more source
Factors associated with student grades in Animal Physiology I [PDF]
Students and faculty alike would like to know what factors are related to success in college courses. The purpose of this study was to evaluate factors that relate to a student’s success in Animal Physiology I (Phys I), an upper-level animal science ...
Hale, Margo, Rosenkrans, Charles
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

