Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
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Why Thai River Fish Occur Where They are Found [PDF]
EnvironmentAsia, 2012 Diversity of freshwater fishes is spatially heterogeneous but, for the most part, the reasons remain poorly understood in Thailand. This review attempts to promulgate factors linking freshwater fishes and habitats, particularly morphological ...
F. William H. Beamish +3 more
doaj
THE RELATIONSHIP OF THE SO-CALLED FAMILY DISEASES TO A PREMATURE PHYSIOLOGICAL SENESCENCE LOCALISED TO CERTAIN ORGANIC SYSTEMS, AND CONSIDERED WITH SPECIAL REFERENCE TO THE NERVOUS SYSTEM. [PDF]
, 1908 F. Lucy Raymond
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
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Memorandum ON THE TREATMENT OF INFECTED WOUNDS BY PHYSIOLOGICAL METHODS. [PDF]
, 1916 A. E. Wright
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
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ON CERTAIN PHYSIOLOGICAL EFFECTS OF STRETCHING OF THE SCIATIC NERVE. [PDF]
, 1881 D BROWNSEQUARD
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Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
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The Physiological Anatomy of Plants: Physiologische pflanzenanatomie, im grundriss dargestellt . Von Dr. G. Haberlandt. Leipzig, Engelmann, 1884. 12+398 p., illustr. 8°. [PDF]
, 1885 G. Macloskie
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