Results 111 to 120 of about 3,860,015 (301)
Journal of Integrative Agriculture, 2017 Rice (Oryza sativa L.) is highly susceptible to the rhizosphere salinity than other cereals. High sensitivity has been observed, mainly at vegetative and reproductive stages in rice.
Sajid Hussain +8 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Total body oxygen stores and physiological diving capacity of California sea lions as a function of sex and age [PDF]
, 2007 Michael J. Weise, Daniel P. Costa
openalex +1 more source
Role of platelet-derived growth factors in physiology and medicine.
Genes & Development, 2008 Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as prototypes for growth factor and receptor tyrosine kinase function for more than 25 years. Studies of PDGFs and PDGFRs in animal development have revealed roles for PDGFR-
Johanna Andrae, R. Gallini, C. Betsholtz
semanticscholar +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Physiology of chimpanzees in orbit. Part 1: Scientific Report [PDF]
Major achievements and accomplishments are reported for the Physiology of Chimpanzees in Orbit Program. Scientific studies relate to behavior and physiology, and engineering studies cover telemetry, behavioral training, systems tests, life support ...
Firstenberg, A., Mcnew, J.
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Investigation of Genotoxicity Caused by Paraben in Albino Mice: Protective Role of Nettle Extract
Cumhuriyet Science Journal, 2017 This studyresearches into the potential physiologic and genotoxic effects of Paraben,which is one of the most frequent chemical substance used in cosmetic and drugsectors, in Swiss Albino mice and the protective role of nettle extract againstthese ...
Baran Seven +4 more
doaj +1 more source