Results 81 to 90 of about 2,780,511 (306)

Innovative Drug Delivery Systems for Management of Menopausal Symptoms: A Systematic Review

open access: yesInternational Journal of Women's Health
Zahra Bostani Khalesi,1 Mahmood Abedinzade,2 Mostafa Golshekan2,3 1Department of Midwifery, Biomedicine Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran; 2Department of Physiology, biomedicine research center, trauma ...
Bostani Khalesi Z   +2 more
doaj  

Editorial: The art of teaching physiology: its place in the integrated curriculum

open access: yesFrontiers in Physiology, 2023
Amberly Reynolds, Irina Nizamutdinova
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

IRBIT a Master Regulator of Cell Physiology [PDF]

open access: yes, 2017
(excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Effects of exercise training on growth and physiology of large-mouth bass (Micropterus salmoides) reared in a recirculating aquaculture system

open access: yesFrontiers in Marine Science
Large-mouth bass originally lived in rivers and lakes and now is often raised in recirculating aquaculture systems (RAS). However, the shortcoming of RAS is that there is very limited space for swimming fish in a high-density culture environment, thus ...
Mingdong Ji, Haijun Li
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Physiology of chimpanzees in orbit. Part 1: Scientific Report [PDF]

open access: yes
Major achievements and accomplishments are reported for the Physiology of Chimpanzees in Orbit Program. Scientific studies relate to behavior and physiology, and engineering studies cover telemetry, behavioral training, systems tests, life support ...
Firstenberg, A., Mcnew, J.
core   +1 more source

Application of the International Centre of Insect Physiology and Ecology (ICIPE) for Inclusion into the CGIAR System [PDF]

open access: yes, 1979
Documents concerning the application of the International Center for Insect Physiology and Ecology (ICIPE) for full CGIAR support and TAC's recommendation against offering such support.
International Centre of Insect Physiology and Ecology
core  

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