Results 1 to 10 of about 77,054 (271)

FGF21 and cardiac physiopathology [PDF]

open access: yesFrontiers in Endocrinology, 2015
The heart is not traditionally considered either a target or a site of fibroblast growth factor-21 (FGF21) production. However, recent findings indicate that FGF21 can act as a cardiomyokine; that is, it is produced by cardiac cells at significant levels
Anna ePlanavila   +2 more
doaj   +4 more sources

In vitro models to study viral-induced asthma exacerbation: a short review for a key issue [PDF]

open access: yesFrontiers in Allergy
Asthma is a heterogenous inflammatory bronchial disease involving complex mechanisms, several inflammatory pathways, and multiples cell-type networks. Bronchial inflammation associated to asthma is consecutive to multiple aggressions on epithelium, such ...
Rémi Pereira De Oliveira   +16 more
doaj   +2 more sources

The Impact of Origanum vulgare Supplementation on Human Asthenozoospermic Sperm Parameter Quality

open access: yesThe Scientific World Journal, 2023
Male infertility is a complex multifactorial disease and a real health problem; 50% of infertile men have identifiable causes detectable by fundamental sperm analysis.
Ahlam Zarhouti   +5 more
doaj   +1 more source

Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]

open access: yes, 2020
Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos   +9 more
core   +3 more sources

STAT3 phosphorylation at serine 727 activates specific genetic programs and promotes clear cell renal cell carcinoma (ccRCC) aggressiveness

open access: yesScientific Reports, 2023
The signal transducer and activator of transcription 3 (STAT3) is a transcription factor mainly activated by phosphorylation in either tyrosine 705 (Y705) or serine 727 (S727) residues that regulates essential processes such as cell differentiation ...
J. Arévalo   +8 more
doaj   +1 more source

Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]

open access: yes, 2020
Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S.   +8 more
core   +1 more source

COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology

open access: yesFrontiers in Physiology, 2021
Smell and taste impairments are recognized as common symptoms in COVID 19 patients even in an asymptomatic phase. Indeed, depending on the country, in up to 85–90% of cases anosmia and dysgeusia are reported.
Nicolas Meunier   +5 more
doaj   +1 more source

Helicobacter pylori infection leads to KLF4 inactivation in gastric cancer through a TET1‐mediated DNA methylation mechanism

open access: yesCancer Medicine, 2020
Krüppel‐like factor 4 (KLF4) has a tumor suppressor role in the progression of gastric cancer (GC), and inhibition or loss of KLF4 expression was identified in GC.
Rongrong Zhao   +7 more
doaj   +1 more source

Successful intravenous immunoglobulin treatment in severe COVID-19 pneumonia

open access: yesIDCases, 2020
We describe a 42-year old woman, admitted to our Department after 15 days of persistence of respiratory failure and treated with infusion of intravenous immunoglobulin with a successful outcome.
Maurizia Lanza   +6 more
doaj   +1 more source

Correlation of Pain and Spasticity with the Quality of Life in Individuals with Spinal Cord Injury [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: After Spinal Cord Injury (SCI), life is associated with risks of many musculoskeletal problems which affect the life of an individual. There is a need for an early assessment for neurological functions and physical activities.
Dilar Amitkumar Rana   +3 more
doaj   +1 more source

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