Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis
Immunology, EarlyView.Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay +4 more
wiley +1 more source
The Physiopathology of T- Cell Acute Lymphoblastic Leukemia: Focus on Molecular Aspects
Frontiers in Oncology, 2020 T-cell acute lymphoblastic leukemia/lymphoma is an aggressive hematological neoplasm whose classification is still based on immunophenotypic findings.
B. Fattizzo +4 more
semanticscholar +1 more source
A termodinâmica como princípio motriz do sistema imune
Einstein (São Paulo)Nos últimos 120 anos, poucas coisas contribuíram tanto para a compreensão do funcionamento do sistema imune quanto o estudo de seu comportamento na relação hospedeiro/parasita.
Eduardo Finger
doaj +1 more source
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons [PDF]
, 2015 Patient-derived induced Pluripotent Stem Cells (iPSCs) provide an opportunity to study human diseases mainly in those cases where no suitable model systems are available.
Bozzoni, Irene +9 more
core +4 more sources
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
EEG Brain Rhythms During Resting‐State Wakefulness and Sleep in Elderly Expert Meditators
Journal of Sleep Research, EarlyView.Compared to controls, elderly expert meditators exhibited (1) more preserved resting‐state brain activity, (2) less altered sleep architecture, and (3) EEG features indicative of heightened cognitive states during NREM sleep. Importantly, several of the metrics that differed between groups also showed consistent correlations with meditation expertise ...
Pierre Champetier +43 more
wiley +1 more source
Understanding the Physiopathology Behind Axial and Radial Diffusivity Changes—What Do We Know?
Frontiers in Neurology, 2018 The use of the diffusion tensor imaging (DTI) is rapidly growing in the neuroimaging field. Nevertheless, rigorously performed quantitative validation of DTI pathologic metrics remains very limited owing to the difficulty in co-registering quantitative ...
P. Winklewski +5 more
semanticscholar +1 more source
Role of the soluble guanylyl cyclase 1 subunit in mice corpus cavernosum smooth muscle relaxation [PDF]
, 2008 C
Brouckaert, Peter +5 more
core +1 more source
Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]
, 2018 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing ...
Ayache, Nicholas +6 more
core +3 more sources
Psychological and Clinical Factors Mediate Post‐COVID‐19 Irritable Bowel Syndrome
Neurogastroenterology &Motility, EarlyView.ABSTRACT Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis of a multicenter cohort study includes 623 patients with and without COVID‐19 infection. All participants
Keren Hod +68 more
wiley +1 more source