Results 61 to 70 of about 780,887 (251)
The Pan African Medical Journal, 2016 Introduction: l'activité physique réguliére a un impact positif sur la santé. Cette étude a pour objet de comparer la condition physique liée à la santé des adultes qui s'exercent librement avec celle des adultes bénéficiant d'un encadrement ...
Jean Berchmans Bizimana +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
PLoS ONE, 2022 Little is known about weight loss practices and eating behaviours in female physique athletes. This study investigated the weight loss history, practices, and key influences during the pre-competition period in a large cohort of female physique athletes ...
Nura Alwan +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Evaluation du niveau d'activité physique dans un service Marocain d'hémodialyse chronique
The Pan African Medical Journal, 2013 INTRODUCTION: L'activité physique est souvent réduite chez le patient hémodialysé chronique. Plusieurs études ont montré l'intérêt du maintien ou de la reprise d'une activité physique sur l'état de santé des patients.
Ilham Karimi +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Revue des Sciences Humaines, 2015 le développement physique est en partie déterminé génétiquement et en partie influencé par le milieu et l'effort musculaire. Le Développement intéresse les changements dans les différentes fonctions de l'organisme, incluant celles qui sont influencées ...
Sabira MAHOUR BACHA FERAHTIA +1 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
BODY ESTEEM AND NARCISSISM AS PREDICTOR OF SOOCIAL PHYSIQUE ANXIETY AMONG ADOOLESCENTS
Pakistan Armed Forces Medical Journal, 2020 Objective: To discover the predicting role of body esteem and narcissism for social physique anxiety among adolescents. Study Design: Correlational study.
Zartasha Qamar +3 more
doaj +4 more sources