Results 61 to 70 of about 570,569 (260)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Nutritional strategies of high level natural bodybuilders during competition preparation
Journal of the International Society of Sports Nutrition, 2018 Background Competitive bodybuilders employ a combination of resistance training, cardiovascular exercise, calorie reduction, supplementation regimes and peaking strategies in order to lose fat mass and maintain fat free mass.
A. J. Chappell, T. Simper, M. E. Barker
doaj +1 more source
Multiple Schramm-Loewner Evolutions and Statistical Mechanics Martingales
, 2005 A statistical mechanics argument relating partition functions to martingales is used to get a condition under which random geometric processes can describe interfaces in 2d statistical mechanics at criticality.
Denis Bernard A +4 more
core +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Revue des Sciences Humaines, 2015 le développement physique est en partie déterminé génétiquement et en partie influencé par le milieu et l'effort musculaire. Le Développement intéresse les changements dans les différentes fonctions de l'organisme, incluant celles qui sont influencées ...
Sabira MAHOUR BACHA FERAHTIA +1 more
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The Pan African Medical Journal, 2016 Introduction: l'activité physique réguliére a un impact positif sur la santé. Cette étude a pour objet de comparer la condition physique liée à la santé des adultes qui s'exercent librement avec celle des adultes bénéficiant d'un encadrement ...
Jean Berchmans Bizimana +3 more
doaj +1 more source
PLoS ONE, 2022 Little is known about weight loss practices and eating behaviours in female physique athletes. This study investigated the weight loss history, practices, and key influences during the pre-competition period in a large cohort of female physique athletes ...
Nura Alwan +4 more
doaj +1 more source