Results 71 to 80 of about 43,583 (238)
Szary Mateusz, Napierała Marek, Pezala Małgorzata, Zukow Walery, Cieśłicka Mirosława, Muszkieta Radosław, Iermakov Sergii, Bartik Pavol, Eksterowicz Jerzy, Stępniak Robert, Karaskova Vlastimila.
Mateusz Szary +10 more
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IntroductionLe but de cet article est d’explorer le lien entre l’activité physique à l’extérieur et la santé mentale, la satisfaction à l’égard de la vie, le bonheur et le stress chez les adolescents canadiens de 12 à 17 ans.
Taylor Bradbury +6 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
La présente étude avait pour but d’explorer l’effet des cours d’éducation physique (ÉP) sur la performance académique des élèves du secondaire.
Charlotte Beaudoin +2 more
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A number of thermometer, anthropometric and psychological characteristics of adult women of Slavic ethnicity is investigated. It is shown that mesendomorphiс index is positively correlated with body weight, massiveness of the skeleton of the lower ...
A. A. Spitsyn
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Social physique anxiety is characterized by feelings of distress experienced when individuals believe they are negatively evaluated on their physique. It could be a risk factor for the development of depressive symptoms.
Tao Zhong
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Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

