Results 81 to 90 of about 780,887 (251)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Penser l’éducation physique autrement
En éducation physique, comme ailleurs, nous avons souvent tendance à nous appuyer sur des pratiques que nous connaissons bien et qui fonctionnent. Cet ouvrage collectif permet de sortir du quotidien de nos classes et de penser autrement en éducation ...
Lentillon-Kaestner, Vanessa
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
La présente étude avait pour but d’explorer l’effet des cours d’éducation physique (ÉP) sur la performance académique des élèves du secondaire.
Charlotte Beaudoin +2 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Szary Mateusz, Napierała Marek, Pezala Małgorzata, Zukow Walery, Cieśłicka Mirosława, Muszkieta Radosław, Iermakov Sergii, Bartik Pavol, Eksterowicz Jerzy, Stępniak Robert, Karaskova Vlastimila.
Mateusz Szary +10 more
doaj
IntroductionLe but de cet article est d’explorer le lien entre l’activité physique à l’extérieur et la santé mentale, la satisfaction à l’égard de la vie, le bonheur et le stress chez les adolescents canadiens de 12 à 17 ans.
Taylor Bradbury +6 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

