Results 101 to 110 of about 570,569 (260)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Study of mesendomorphy index relationship with skin surface temperature and accentuation (by the Leonhard-Shmishek test) in adult women of Slavic ETHNICITY

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
A number of thermometer, anthropometric and psychological characteristics of adult women of Slavic ethnicity is investigated. It is shown that mesendomorphiс index is positively correlated with body weight, massiveness of the skeleton of the lower ...
A. A. Spitsyn
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The Association Between Social Physique Anxiety and Depressive Symptoms in Young Adults: The Mediating Effect of Psychological Resilience and the Moderating Effect of Gender

SAGE Open
Social physique anxiety is characterized by feelings of distress experienced when individuals believe they are negatively evaluated on their physique. It could be a risk factor for the development of depressive symptoms.
Tao Zhong
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

BODY ESTEEM AND NARCISSISM AS PREDICTOR OF SOOCIAL PHYSIQUE ANXIETY AMONG ADOOLESCENTS

Pakistan Armed Forces Medical Journal, 2020
Objective: To discover the predicting role of body esteem and narcissism for social physique anxiety among adolescents. Study Design: Correlational study.
Zartasha Qamar, Najma Iqbal Malik, Aneela Maqsood, Shoaib Kiani   +3 more
doaj  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Niveaux d’activité physique des Canadiens sous l’angle de l’équité en matière de santé

Promotion de la santé et prévention des maladies chroniques au Canada
IntroductionCette étude a porté sur l’activité physique chez les jeunes (12 à 17 ans) et chez les adultes (18 ans et plus) vivant au Canada, en fonction de différentes catégories (genre, orientation sexuelle, groupes de population ...
Justin J. Lang, Sarah E. Turner, Natalie Doan, Iryna Demchenko, Stephanie A. Prince, Karen C. Roberts, Marisol T. Betancourt, Rachel Colley, Rabina Jahan, Ashley Amson, Jean-Philippe Chaput   +10 more
doaj   +1 more source

New Charm Results from Focus

, 2004
New results from the photoproduction experiment FOCUS are reported: Dalitz plot analysis, semileptonic form factor ratios and excited meson spectroscopy.Comment: 8 pages, 5 figures, Frascati preprint style lnfprep.sty (included).
Bianco, S.
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source