Results 91 to 100 of about 570,569 (260)

Histoires de réussite : L’effet du cours d’éducation physique sur la performance académique d’élèves franco-ontarien, en dixième année du secondaire

open access: yeseJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2005
La présente étude avait pour but d’explorer l’effet des cours d’éducation physique (ÉP) sur la performance académique des élèves du secondaire.
Charlotte Beaudoin   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Forward-Backward Asymmetry in NNLO QCD [PDF]

open access: yes, 1999
We have recently calculated the second-order QCD corrections to the forward-backward asymmetry in e+e- annihilation (hep-ph/9905424). Here we recall the results and compare them to others in the literature.Comment: 14 pages, LaTeX, uses lathuile.sty ...
Catani, Stefano, Seymour, Michael H.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Stan cech somatycznych i sprawność ogólna uczniów w wieku 17 lat z centrum kształcenia zawodowego i ustawicznego w Więcborku = Somatic features state and general performance of pupils aged 17 years with centre of vocational training and learning in Wiecbo

open access: yesJournal of Education, Health and Sport, 2015
Szary Mateusz, Napierała Marek, Pezala Małgorzata, Zukow Walery, Cieśłicka Mirosława, Muszkieta Radosław, Iermakov Sergii, Bartik Pavol, Eksterowicz Jerzy, Stępniak Robert, Karaskova Vlastimila.
Mateusz Szary   +10 more
doaj  

Top Quark Mass Measurements at the Tevatron

open access: yes, 2008
Top quark mass measurements from the Tevatron using up to \invfb{2.0} of data are presented. Prospects for combined Tevatron measurements by the end of Run II are discussed.Comment: 8 pages, Proceedings 22nd Les Rencontres de Physique de la Vallee d ...
Adelman, Jahred
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Activité physique à l’extérieur, santé mentale, satisfaction à l’égard de la vie, bonheur et stress chez les adolescents canadiens

open access: yesPromotion de la santé et prévention des maladies chroniques au Canada
IntroductionLe but de cet article est d’explorer le lien entre l’activité physique à l’extérieur et la santé mentale, la satisfaction à l’égard de la vie, le bonheur et le stress chez les adolescents canadiens de 12 à 17 ans.
Taylor Bradbury   +6 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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