Results 111 to 120 of about 7,017 (216)

Open field behavior in nucleus basalis magnocellularis-lesioned rats treated with physostigmine and verapamil

open access: yes, 1997
The present study was done to investigate and compare the effect of acetylcholinesterase inhibitor, physostigmine (0.030, 0.045, 0.060 and 0.075 mg/kg sc) and Ca-antagonist, verapamil (1.0, 2.5, 5.0 and 10.0 mg/kg sc) on open field behavior in male ...
Popović, M.   +5 more
core   +1 more source

Antimuscarinic delirium in a pediatric patient reversed with transdermal rivastigmine: A case report

open access: yesJEM Reports
Background: Antidotal treatment of antimuscarinic delirium (AMD) standardly involves parenteral administration of physostigmine. However, due to cessation of physostigmine production, administration of oral or transdermal rivastigmine may serve as a ...
Natalie E. Ebeling-Koning   +5 more
doaj   +1 more source

Pharmacological evaluation of an injectable prolonged release emulsion of physostigmine in rabbits

open access: yes, 1986
Physostigmine was incorporated in an injectable emulsion in an attempt to prolong its pharmacological activity. Emulsions which remained stable over 6 month storage were prepared using optimal experimental conditions.
Marta Weinstock   +2 more
core   +1 more source

Tetrahydroaminoacridine and Physostigmine Increase Cerebral Glucose Utilization in Specific Cortical and Subcortical Regions in the Rat

open access: yes, 1993
The effects of the anticholinesterases tetrahydroaminoacridine (THA) and physostigmine on local cerebral glucose utilization (LCGU) were studied in the conscious rat, using the autoradiographic [14C]deoxyglucose technique.
F. Jazat, M. H. Bassant, Y. Lamour
core   +1 more source

Antagonism of morphine-induced central respiratory depression by donepezil in the anesthetized rabbit

open access: yesBiological Research, 2007
Morphine is often used in cancer pain and postoperative analgesic management but induces respiratory depression. Therefore, there is an ongoing search for drug candidates that can antagonize morphine-induced respiratory depression but have no effect on ...
MIKI TSUJITA   +8 more
doaj  

Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling [PDF]

open access: yes, 2019
Background In the context of the cholinergic anti-inflammatory pathway, the clinical trial Anticholium® per Se (EudraCT Number: 2012-001650-26, ClinicalTrials.gov NCT03013322) addressed the possibility of taking adjunctive physostigmine salicylate ...
Hempel, G   +8 more
core  

Toxicology of physostigmine

open access: yes, 2012
Tato bakalářská práce se zabývá problematikou alkaloidu fyzostigminu, který je produkován rostlinou z čeledi bobovitých (Fabaceae) jménem puchýřnatec jedovatý (Physostigma venenosum).This bachelor thesis is dealt with question of alkaloid physostigmine,
Trousil, Vojtěch
core  

Safety and Efficacy of Oral Physostigmine in the Treatment of Alzheimer Disease

open access: yes, 1993
Results of therapeutic trials with physostigmine in the treatment of Alzheimer disease (AD) have been inconsistent and controversy persists concerning safety and efficacy.
Sano, Mary   +8 more
core   +1 more source

Central injection of physostigmine attenuates exercise-induced pressor response in conscious cats

open access: yes, 1997
The effects of intracerebroventricular administration of physostigmine, a cholinesterase inhibitor, on the cardiovascular responses evoked by static voluntary exercise were investigated using conscious cats.
G. A. Hand, J. H. Mitchell, A. Ally
core   +1 more source

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