Results 91 to 100 of about 7,017 (216)

Effect of Ganoderma lucidum on memory and learning in mice

Clinical Phytoscience, 2019
Background In traditional Chinese medicine Ganoderma lucidum is famous for its beneficial effect on nervous system. It was traditionally used to manage different neurological disorders.
Najeeb Khatian, Muhammad Aslam
doaj   +1 more source

The cholinesterase inhibitor physostigmine for the local treatment of dry mouth: a randomized study

, 2009
Application of physostigmine to the oromucosal surface with the aim of stimulating underlying mucin-producing glands while reducing cholinergic systemic effects might be a strategy for treating dry mouth.
Khosravani, Nina,, Birkhed, Dowen,, Ekström, Jörgen,   +2 more
core   +1 more source

Pediatric Anticholinergic Toxidrome and Treatment with Physostigmine

, 2019
Background and Hypothesis: Physostigmine is the antidote to anticholinergic poisoning. Widely used in the 1970s, 2 cases published in 1980 associated use of physostigmine with significant adverse cardiotoxic events.
Avera, MD, Bob, Nanagas MD, Kristine, Overberg PharmD, BCPS, CSPI, Adam, Morton, MPH, Shannon, Huber, Sarah   +4 more
core  

Study of anti-nociceptive potential of physostigmine and its combination with morphine in albino rats

, 2017
Background: The cholinergic drugs are having antinociceptive potential but are under investigation because of their serious side effects. It is difficult to accept them as an analgesic.
Bite, Bapurao M., Chaudhari, Devendra R., Bhavasar, Rahul P., Chopade, Suyog S.   +3 more
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Inhibition of acetylcholinesterase from electric eel by (−)- and (+)-physostigmine and related compounds

, 1986
Unnatural (+)-physostigmine (2) inhibited acetylcholinesterase (AChE) from electric eel considerably less than natural (−)-physostigmine (1), but 2 may because of its possible lower toxicity still be an interesting anticholinesterase agent. (−)-Eseroline
Schönenberger, B., R. Ray, A. Brossi, Ray, R., Brossi, A., O.E. Clark, B. Schönenberger, Clark, O.E.   +7 more
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Novel synthesis of physovenine and physostigmine analogs

, 2016
This Letter describes a versatile synthetic approach to prepare physovenine and physostigmine analogs. A series of analogs were synthesized and evaluated for cholinesterase inhibition activities, including human acetylcholinesterase (AChE) and ...
Nikogosyan, G., Decarlo, C., Zhang, L. K., Wang, C. H., White, A. R., Mabagos, G., Ganguly, A. K., Feng, H. H., ANDRISANO, VINCENZA, Alluri, S., Monteiro, C., BARTOLINI, MANUELA   +11 more
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Physostigmine: A Plant Alkaloid Isolated from Physostigma venenosum: A Review on Pharmacokinetics, Pharmacological and Toxicological Activities

, 2020
Medicinal plants have been documented as an important source for discovering new pharmaceutical molecules that have been used to treat serious diseases. Strikingly, previous reports stated that natural products and their derived compounds exhibit lesser ...
Nadwa, Eman H., Shaheen, Hazem, Alkazmi, Luay M., Beshbishy, Amany Magdy, Rashwan, Eman K., Wasef, Lamiaa, Batiha, Gaber El-Saber   +6 more
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Involvement of cholinergic system in state-dependent learning induced by lithium in mice [PDF]

Iranian Journal of Psychiatry, 2008
"nObjective:The influence of cholinergic drugs on lithium-induced statedependent learning has been investigated in adult male mice. "nMethod: A single-trial step-down inhibitory avoidance task was selected.
Vahedeh Toosi, Fatemeh Mollahasani, Mohammad-Reza Zarrindast, Shamseddin Ahmad   +3 more
doaj   +2 more sources

Clinical outcomes in children with hyoscyamus niger intoxication no receiving physostigmine therapy

, 2007
Objective Diagnosis of hyoscyamus niger intoxication is based on clinical symptomatology and history. Therapy includes stomach lavage, supportive therapy, and physostigmine as a specific antidote. Physostigmine is not available in Turkey.
Orbak, Zerrin, Karakelleoglu, Cahit, Doneray, Hakan   +2 more
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Comparative effects of physostigmine and neostigmine on acquisition and performance of a conditioned avoidance behavior in the rat [PDF]

, 1974
The actions of physostigmine (0.10 and 0.15 mg/kg) and neostigmine (0.12 mg/kg) given s.c. on acquisition and performance of conditioned pole jumping were studied in rats receiving either 0.9% saline, (-) hyoscyamine or atropine methylnitrate.
Rosecrans, John A., Domino, Edward F.
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