Results 71 to 80 of about 7,017 (216)

The Carbamate, Physostigmine does not Impair Axonal Transport in Rat Cortical Neurons

Neuroscience Insights, 2021
Among the various chemicals that are commonly used as pesticides, organophosphates (OPs), and to a lesser extent, carbamates, are most frequently associated with adverse long-term neurological consequences.
Sean X Naughton, Wayne D Beck, Zhe Wei, Guangyu Wu, Peter W Baas, Alvin V Terry   +5 more
doaj   +1 more source

Effects of physostigmine on rat brain acetylcholine, acetylcholinesterase and conditioned pole jumping, [PDF]

, 1968
The present study was designed to provide evidence that the behavioral effects of physostigmine are related to inhibition of brain acetylcholinesterase (AChE). Adult male Holtzman rats were trained to pole jump to a buzzer as the conditioned stimulus and
Dren, Anthony T., Rosecrans, John A., Domino, Edward F.   +2 more
core   +1 more source

Interaction of physostigmine with three injectable anaesthetics in a young chick model

Bulgarian Journal of Veterinary Medicine
Propofol, thiopental and ketamine are injectable general anaesthetics with different mechanisms of action. Reports vary with respect to the antagonistic action of physostigmine against these anaesthe¬tics.
H. M. S. Garmavy, F. K. Mohammad
doaj   +1 more source

Heroin Adulterated with the Novel Synthetic Cannabinoid, 5F-MDMB-PINACA: A Case Series

Clinical Practice and Cases in Emergency Medicine, 2020
Introduction: Heroin can be adulterated with various substances that may or may not have pharmacological effects. Here we report a case series of 8 patients who presented to the emergency department after overdose with intravenous heroin preparation ...
Muhammed Ershad, Maricel Dela Cruz, Ahmed Mostafa, Muhammad M. Khalid, Ryan Arnold, Richard Hamilton   +5 more
doaj   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Reversal of cognitive impairment by heptyl physostigmine, a long-lasting cholinesterase inhibitor, in primates.

, 1992
Cholinergic replacement therapy for Alzheimer's disease using existing cholinesterase inhibitors is compromised by short duration, meagre benefits restricted to subgroups of patients, and peripheral toxicity.
Heald, A, Tye, SJ, Rupniak, NM, Brazell, C, Iversen, Susan, Pagella, PG   +5 more
core   +1 more source

Green Coffee Bean Extract Mitigates Alzheimer’s Disease in Male Rats

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Green coffee bean extract (GCBE) has shown potential for antioxidants and anti‐inflammation due to its rich composition of bioactive compounds and polyphenols that possess neuroprotective properties, which have been suggested to counteract neurodegenerative processes associated with Alzheimer’s disease (AD).
Amal S. Abu-Almakarem, Othman R. Alzahrani, Rasha Abu-Khudir, S. R. Alassar, Karim Samy El-Said, Sahar Abdulrahman Alkhodair, Abeer A. Banjabi, Maha M. Al-Bazi, Maysa A. Mobasher, Mohamed Mostafa Soliman, Anupama Bose   +10 more
wiley   +1 more source

Habituation Should Be Measured Directly: Effects of Physostigmine on Activity

, 1977
The effect of 0.1 and 0.25 mg/kg physostigmine on the rate of habituation of ambulation, rearing and grooming in rats tested in a 36- × 36-in. open field was investigated.
Nancy Stewart, Warren Stewart
core   +1 more source

Overview of acute Chinese medicine poisoning in Hong Kong

Hong Kong Journal of Emergency Medicine, Volume 32, Issue 6, December 2025.
Abstract Background Chinese medicine (CM) poisoning is relatively rare in Hong Kong. According to the Department of Health, only 17 cases of self‐medicated Traditional Chinese Medicine (TCM)‐related poisoning were reported between 2019 and 2021—an average of approximately 5.7 cases per year.
Siu Kan Law, Yanping Wang, Xiao Xiao Wu
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source