Results 51 to 60 of about 7,017 (216)

Successful Treatment of Immune Checkpoint Inhibitor‐Induced Myocarditis, Myositis, and Myasthenia Overlap Syndrome With Baricitinib and Abatacept

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Immune checkpoint inhibitor (ICI) therapies are known to cause immune‐related adverse events (irAEs), including life‐threatening myocarditis, myositis, and myasthenia (MMM) overlap syndrome. Current literature lacks established therapeutic guidelines for effective management with steroid‐sparing agents.
Zeinab Alnahas, Sujata Sarkar, Oishi Roychoudhury, Ernest Algabre   +3 more
wiley   +1 more source

Quantitative determination of physostigmine in solution

, 1967
A chemical assay is described for the indirect determination of physostigmine (eserine) in solution. The method involves a chemical reaction between methylamine, a hydrolysis product of physostigmine, and carbon disulphide to form a dithiocarbamic acid ...
F W TEARE, D W TAYLOR
core   +1 more source

Evaluation of Agave angustifolia as a Sustainable Alternative to Synthetic Pesticides: Phytochemical Composition and Multi‐Trophic Bioactivity

Flavour and Fragrance Journal, Volume 41, Issue 3, Page 656-672, May 2026.
The pesticidal potential of Agave angustifolia by assessing its anti‐nematic, antimicrobial, and insecticidal activities, alongside phytochemical profiling. ABSTRACT Plant diseases caused by fungi, bacteria, nematodes, and viruses contribute significantly to annual crop losses and economic hardship. Reliance on chemical pesticides, over a thousand used
Rashika Tamta, Shilpi Rawat, Himani Karakoti, Tannu Rani, Pooja Bargali, Ravendra Kumar, Stefania Garzoli, Renu Pandey   +7 more
wiley   +1 more source

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

FEBS Open Bio, 2014
Although fasting induces hepatic triglyceride (TG) accumulation in both rodents and humans, little is known about the underlying mechanism. Because parasympathetic nervous system activity tends to attenuate the secretion of very-low-density-lipoprotein ...
Shin-Ichi Yokota, Kaai Nakamura, Midori Ando, Hiroyasu Kamei, Fumihiko Hakuno, Shin-Ichiro Takahashi, Shigenobu Shibata   +6 more
doaj   +1 more source

Quantitative determination of physostigmine from aqueous solution

, 1969
A gas chromatographic method is described for the direct determination of physostigmine base from a solution of physostigmine salicylate. The method involves isolation of physostigmine salicylate from an aqueous solution by a freeze drying process ...
F W Teare, S I Borst
core   +1 more source

The Contribution to the Assignment of Defined Daily Dose (DDD) to Antineoplastic Drugs of the Italian Working Group on DDD

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose To report the experience of the Italian Working Group on DDD (Ita‐DDD‐wg) in assigning DDDs to a list of antineoplastic agents. Methods Active substances from the ATC L01 group with no assigned DDD and reimbursed at least once during 2021 by the Italian Healthcare Service were identified.
Angela Boccia, Giulia Hyeraci, Anna Girardi, Rosa Gini, Gianluca Trifirò, Ylenia Ingrasciotta, Andrea Spini, Valentina Ientile, Elisabetta Poluzzi, Giampiero Mazzaglia, Ippazio Cosimo Antonazzo, Casula Manuela, Elena Tragni, Olivia Leoni, Arianna Mazzone, Michele Ercolanoni, Martina Zanforlini, Ursula Kirchmayer, Belleudi Valeria, Marco Finocchietti, Francesco Barone‐Adesi, Giuseppe Roberto   +21 more
wiley   +1 more source

Adverse Effects of Physostigmine [PDF]

Journal of Medical Toxicology, 2019
Physostigmine is a tertiary amine carbamate acetylcholinesterase inhibitor. Its ability to cross the blood-brain barrier makes it an effective antidote to reverse anticholinergic delirium. Physostigmine is underutilized following the publication of patients with sudden cardiac arrest after physostigmine administration in patients with tricyclic ...
Ann M, Arens, Tom, Kearney
openaire   +2 more sources

Effects of Oral Physostigmine in Alzheimer's Disease

, 1987
Previous studies of oral physostigmine in the treatment of Alzheimer's disease have: (1) assumed physostigmine is effective only in mildly affected patients; (2) relied on an initial “dose-finding” phase to determine the most effective dose and excluded ...
Sano, Mary, Stern, Yaakov, Yaakov Stern, Mary Sano, Mayeux, Richard Paul, Richard Mayeux   +5 more
core   +1 more source

Effect of the Carbamate (Physostigmine) on the Activity of Nitric Oxide Synthase in Different Parts of Rat Brain (In Vivo Studies)

Journal of High Institute of Public Health, 2007
Physostigmine (eserine) is the methyl carbamic ester of phenolic trimethyl ammonium compound. It is a powerful inhibitor of acetylcholinesterase enzyme activity and used in some therapeutic preparation.
Hassan M.Y. Osman
doaj   +1 more source

Adjunctive use of physostigmine salicylate (Anticholium®) in perioperative sepsis and septic shock: study protocol for a randomized, double-blind, placebo-controlled, monocentric trial (Anticholium® per Se)

Trials, 2017
Background Severe sepsis and septic shock remain a major challenge, even in modern intensive care. In Germany, about 68,000 patients die annually because of septic diseases, characterized by a complex systemic inflammatory response.
Johannes B. Zimmermann, Nadine Pinder, Thomas Bruckner, Monika Lehmann, Johann Motsch, Thorsten Brenner, Torsten Hoppe-Tichy, Stefanie Swoboda, Markus A. Weigand, Stefan Hofer   +9 more
doaj   +1 more source