Results 111 to 120 of about 291,099 (263)

Phytochemicals in structure-based drug discovery

, 2023
Plants in general are a dominant source of bioactive compounds that produce new chemical entities with the potential to cure or prevent several human diseases and infections.
Barse B., Kumar A., Floris S., Di Petrillo A., Baranwal J., Fais A.   +5 more
core   +1 more source

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

Animal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu, Samantha Howe, Yang Tian, Alisun N. Watson, Jason E. Farrar, Christopher E. Randolph, Jaime Andrés Ángel Isaza, Álvaro José Uribe, Yan Huang, Michael Looper, Jiangchao Zhao, Tsungcheng Tsai   +11 more
wiley   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Limited hypersensitive response but enhanced lignin synthesis leads to Pseudomonas syringae pv. actinidiae tolerance in Actinidia eriantha

Horticulture Advances
Kiwifruit bacterial canker, caused by Pseudomonas syringae pv. actinidiae (Psa), poses a significant threat to the kiwifruit industry. Certain kiwifruit species, such as Eri-1 (Actinidia eriantha), exhibit resistance to Psa, as indicated by the minimal ...
Jianyou Gao, Cuixia Liu, Jiewei Li, Li Li, Beibei Qi, Hongjuan Gong, Liming Xia, Rongxiang Zhu, Quanhui Mo, Qiaosheng Jiang, Kaiyu Ye, Faming Wang   +11 more
doaj   +1 more source

Plant-Based Phytochemicals as Possible Alternative to Antibiotics in Combating Bacterial Drug Resistance

Antibiotics, 2020
The unprecedented use of antibiotics that led to development of resistance affect human health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases progressed with the acquisition and as such development of antibiotic
Hana Mohammed Al Alsheikh, Insha Sultan, V. Kumar, I. Rather, Hashem Al-Sheikh, Arif Tasleem Jan, Q. M. R. Haq   +6 more
semanticscholar   +1 more source

Effects of Phytochemicals on Atherosclerosis: Based on the Gut–Liver Axis

Background: Atherosclerosis (AS) is the primary pathological basis for cardiovascular and cerebrovascular events, with its development closely linked to dyslipidemia and chronic inflammation.
Weiwei Cui, Yiming Wang, Cui, Weiwei, Wang, Yiming   +3 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Functional Characteristics of Fungal Communities in the Rhizosphere of the Endangered Plant Abies ziyuanensis

Microorganisms
First discovered in 1977, Abies ziyuanensis (Pinaceae) is listed as an endangered species by the International Union for Conservation of Nature (IUCN); its population continues to decline.
Yufeng Wang, Jiahao Wu, Tao Deng, Jiatong Ye, Xinghua Hu   +4 more
doaj   +1 more source

Recent Research on the Role of Phytochemicals from Ginseng in Management of Osteosarcoma, Osteoporosis, and Osteoarthritis

Ginseng phytochemicals have attracted considerable attention for their potential therapeutic applications in bone-related diseases including osteosarcoma, osteoporosis, and osteoarthritis.
See-Hyoung Park
core   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source