Results 51 to 60 of about 9,812 (163)

Association Between Dietary Anthocyanidin Intake and Thyroid Autoimmunity: A Cross‐Sectional Study From NHANES (2007–2010)

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Despite extensive documentation of the immunomodulatory effects of anthocyanidins, population‐based epidemiological studies have yet to elucidate their association with thyroid autoimmunity (TAI). Methods Using flavonoid intake data from the Flavonoid and Anthocyanidin Database (FNDDS) and 2007–2010 National Health and Nutrition ...
Mingkuan Chen, Yirong Yuan, Yuan Zhao, Siyu Wu, Haitao Yang, Dun Xiong, Shaocai Xia   +6 more
wiley   +1 more source

Excessive levels of diverse phytoestrogens can modulate steroidogenesis and cell migration of KGN human granulosa-derived tumor cells

Toxicology Reports, 2014
Phytoestrogens are plant-derived estrogen-like compounds that are increasingly used for their suggested health promoting properties, even by healthy, young women.
Kamila A. Solak, Fiona M.J. Wijnolts, Sandra M. Nijmeijer, Bas J. Blaauboer, Martin van den Berg, Majorie B.M. van Duursen   +5 more
doaj   +1 more source

Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak, Rachael Moorin, Jeff Hughes, Karl Gruber, David Youens   +4 more
wiley   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, Volume 293, Issue 15, Page 4624-4644, August 2026.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

The Importance of Phytoestrogens in Food Supplements and Phytopharmaceuticals

CHIMIA, 2005
Different natural products from the plant kingdom including isoflavones, prenylflavones, coumestans, stilbenes, and lignans can cause endocrine perturbations, especially on the estrogenic hormonal pathway because of their structural analogies to
Johanne Polasek, Kurt Hostettmann
doaj   +1 more source

Enduring autism‐like phenotypes and deregulated hypothalamic prosocial peptides after early‐life exposure to indoor flame retardants in male C57BL/6 mice

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract Polybrominated diphenyl ethers (PBDEs) are neuroendocrine‐disrupting chemicals that produce adverse neurodevelopmental effects. PBDEs have been implicated as risk factors for autism spectrum disorder (ASD), which is characterized by abnormal psychosocial functioning and is commonly comorbid with cognitive deficits and sensory abnormalities ...
Elena V. Kozlova, Gwendolyn M. Gonzalez, Maximillian E. Denys, Anthony E. Bishay, Roberto Gutierrez, Jack Reid, Julia M. Krum, Gregory Lampel, Naran Luvsanravdan, Kayhon M. Rabbani, Jordan Tu, Luis Campoy, Laura M. Anchondo, Crystal N. Luna, Duraan S. Olomi, Eduardo Monarrez, Valeria Carrillo, Jasmin D. Tran, Damon Platt, Yash Korde, Bhuvaneswari D. Chinthirla, Maher Blaibel, Simon Kim, Gladys Chompre, Allison L. Phillips, Heather M. Stapleton, Bernhard Henkelmann, Karl‐Werner Schramm, Margarita C. Curras‐Collazo   +28 more
wiley   +1 more source

Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats

Nutrition & Metabolism, 2010
Background Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors.
Kaphalia Bhupendra S, Nauduri Dhananjaya, Kochukov Mikhail, Jeng Yow-Jiun, Watson Cheryl S   +4 more
doaj   +1 more source

Association between Spot urine Phytoestrogens as Biomarkers on Their Dietary Intake on the Risk of Death from Cancer and Cardiovascular Disease [PDF]

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt, 2017
This study suggests that phytoestrogen intake alters cancer and cardiovascular risk. This study investigated the associations of urinary phytoestrogens with total cancer (n = 198), cardiovascular (n = 152), and all-cause (n = 363) mortality among 5179 ...
Gamil Mahmud, Jones Zhang, Kathryn Josette, Jones Else, Shahat S.   +4 more
doaj   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

Elevated temperature and increased precipitation alter isoflavone concentrations and biomass of red clover

Crop Science, Volume 66, Issue 4, July/August 2026.
Abstract Red clover (Trifolium pratense L.) is a widely grown perennial forage legume that supports sustainable livestock production through its high nutritive value and bioactive isoflavones. Future climate change, particularly warming and increased rainfall, may influence forage accumulation and isoflavone concentrations.
Palash Mandal, Rebecca K. McGrail, Jim A. Nelson, John B. May, A. Elizabeth Carlisle, Rebecca L. McCulley   +5 more
wiley   +1 more source