Food Frontiers, Volume 7, Issue 1, January 2026.The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
The phenolic complex in flaxseed [PDF]
, 2008 Flaxseed is the richest plant source of the lignan secoisolariciresinol diglucoside (SDG). In flaxseed, SDG exists in an oligomeric structure with 3-hydroxy-3-methyl glutaric acid (HMGA) forming a phenolic complex together with p-coumaric acid and ...
Strandås, Christina
core
Dietary isoflavones alter regulatory behaviors, metabolic hormones and neuroendocrine function in Long-Evans male rats [PDF]
, 2004 Background Phytoestrogens derived from soy foods (or isoflavones) have received prevalent usage due to their 'health benefits' of decreasing: a) age-related diseases, b) hormone-dependent cancers and c) postmenopausal symptoms.
Bu Lihong +6 more
core +2 more sources
Phytoestrogens: Food or Drug? [PDF]
, 2006 Within the past several years, the relation between diet and health has been accepted by the mainstream nutrition community and in this connection interest in the physiological role of bioactive compounds present in plants has dramatically increased over the last decade.The phytoestrogens are bioactive molecules present as nutritional constituents of ...
BACCIOTTINI, LUCIA +5 more
openaire +3 more sources
Effect of oral genistein administration in early and late phases of allergic encephalomyelitis [PDF]
, 2014 Objective(s): Experimental allergic encephalomyelitis (EAE) is an autoimmune disease validated as animal model of multiple sclerosis (MS). Administration of genistein, a phytoestrogenic component of soy, to mice at the onset of EAE is known to attenuate ...
Alizadeh, A. +5 more
core +1 more source
High intake of phytoestrogens and precocious thelarche: case report with a possible correlation [PDF]
, 2007 Precocious thelarche is the breast development before 8 years of age with two peaks of incidence during the first two years of life and after 6 years of age.
Adlercreutz M +25 more
core +3 more sources
Phytoestrogens in treatment of climacteric syndrome as an alternative to menopausal hormone therapy
Акушерство, гинекология и репродукция, 2020 Russian and international literature over the last 5 years was observed to study the use of phytoestrogens in treatment of climacteric syndrome. Effects of isoflavones as the main group of phytoestrogens on vasomotor, cognitive, psychological, urogenital
M. I. Mazitova +2 more
doaj
The positive association of lignan and flavonoid intakes with bone mineral density (BMD) in men from Southern China [PDF]
, 2012 OBJECTIVE(S): There have been promising data showing that phytoestrogens may prevent bone loss in postmenopausal women. However there has been little data on the skeletal effect of specific phytoestrogens among young men and premenopausal women.
Cheung, CL +4 more
core
EFFECTS OF PHYTOESTROGENS ON MAMMALIAN REPRODUCTIVE PHYSIOLOGY
Tropical and Subtropical Agroecosystems, 2011 Global consumption of phytoestrogens and their effects have increased both in animals and humans due to the augmented use of legumes in animal diets as well as the increase in vegetarian diets in some human populations.
Socorro Retana-Márquez +9 more
doaj
Phytoestrogen Genistein and Black Cohosh and Marker of BMD in Menopausal Women [PDF]
, 2012 Background: In Indonesia, phytoestrogens can be found in the market as supplement to resolve climacteric complaint and osteoporosis. This phytoestrogens has not been proven scientifically to have benefit in overcoming the climacteric complaints and ...
Abadi, A. (Adenan) +3 more
core