Results 61 to 70 of about 880,343 (275)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The Stability Analysis for a 2 × 2 Conservation Law with PI Controller and PDP Controller

Journal of Mathematics, 2023
This article is concerned with the stability analysis of a 2×2 conservation law with PI and PDP boundary feedback control. In the PI controller case, the authors establish a sufficient and necessary stability condition for feedback parameters by Walton ...
Dong-Xia Zhao, Fang-Xia Bao
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Multifaceted effects of soluble human CD6 in experimental cancer models

Journal for ImmunoTherapy of Cancer, 2020
Background CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse.
Inês T Simões, Fernando Aranda, Sergi Casadó-Llombart, María Velasco-de Andrés, Cristina Català, Pilar Álvarez, Marta Consuegra-Fernández, Marc Orta-Mascaró, Ramón Merino, Jesús Merino, José Alberola-Ila, Gloria González-Aseguinolaza, Esther Carreras, Vanesa Martínez, Francisco Lozano   +14 more
doaj   +1 more source

dayside Pi 2 pulsations at low latitudes

Geophysical Research Letters, 1989
In this paper we investigate the occurrence of dayside Pi 2 geomagnetic pulsations at low and mid latitudes. The technique of data adaptive filtering is used to identify Pi 2's concealed by the presence of typical daytime Pc type pulsations. Convincing new evidence is presented demonstrating that Pi 2 pulsations occur simultaneously in both the ...
Peter R. Sutcliffe, Kiyohumi Yumoto
openaire   +1 more source

The Froissart bound for inelastic cross-sections

, 2009
We prove that while the total cross{}-section is bounded by $(\pi/m_\pi^2) \ln^2 s$, where $s$ is the square of the c.m. energy and $m_\pi$ the mass of the pion, the total inelastic cross{}-section is bounded by $(1/4)(\pi/m_\pi^2) \ln^2 s$, which is 4 ...
Martin, André
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

An Exact Diagonalization Demonstration of Incommensurability and Rigid Band Filling for N Holes in the t-J Model

, 1993
We have calculated S(q) and the single particle distribution function for N holes in the t - J model on a non--square sqrt{8} X sqrt{32} 16--site lattice with periodic boundary conditions; we justify the use of this lattice in compariosn to those of ...
A. Aharony, A. Moreo, A. Moreo, A. Singh, B. Keimer, B.I. Shraiman, B.I. Shraiman, B.S. Shastry, C.L. Kane, C.L. Kane, D. Poilblanc, D.M. Frenkel, E. Dagotto, E. Dagotto, E.R. Gagliano, F.C. Chou, F.C. Zhang, H. Q. Ding, H.J Schulz, H.J Schulz, H.J. Schultz, J. Zaanen, J.H. Cho, J.M. Luttinger, J.M. Luttinger, J.M. Luttinger, K. J. E. Vos, K.J. Szczepanski, K.M. Rabe, M. Inui, M.S. Hybertsen, P. Bénard, P. W. Leung, P.W. Anderson, P.W. Leung, R. J. Gooding, R. Liu, R.J. Gooding, R.J. Gooding, R.J. Gooding, R.J. Gooding, S. W. Cheong, S.A. Trugman, S.A. Trugman, T.E. Mason, T.E. Mason, T.R. Thurston, W. Stephan   +47 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Systematic 1/S study of the 2D Hubbard model at half-filling

, 1994
The 2D Hubbard model is extended by placing 2S orbitals at each lattice site and studied in a systematic 1/S expansion. The 1/S results for the magnetic susceptibility and the spectra of spin-wave excitations at half-filling are consistent with the large
A. Chubukov, A. Singh, A. Singh, A. Singh, A.V. Chubukov, Andrey V. Chubukov, B. Keimer, B.I. Halperin, B.I. Shraiman, B.I. Shraiman, C. Gros, C. L. Kane, D. Forster, D.J. Scalapino, E. Dagotto, G. Vignale, H. Monien, I. Affleck, J. E. Hirsch, J. Igarashi, J.D. Reger, J.R. Schrieffer, Karen A. Musaelian, M. Boninsegni, P. Montoux, R.R.P. Singh, R.R.P. Singh, S. Chakravarty, S. John, S. John, S. Sachdev, S. Trugman, T. Oguchi   +32 more
core   +1 more source