Results 91 to 100 of about 10,466,988 (282)

Adolescents’ Psychological Inflexibility as a Mediator Between Maternal Inflexibility and Internalizing Problems

open access: yesChildren
Background/Objectives: Internalizing disorders are highly prevalent during adolescence. Previous research has shown that psychological inflexibility (PI) in both adolescents and their parents contributes to internalizing problems.
Luisa Fanciullacci   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Effect of Hepatitis C Virus Genotype, Cirrhosis, and Viral Cure on Serum Phosphatidylinositol Species Profiles

open access: yesBiomedicines
Background/Objectives: Phosphatidylinositol (PI) species are bioactive lipids implicated in liver fibrogenesis. Hepatitis C virus (HCV) relies on host lipid metabolism for infection.
Kilian Weigand   +6 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Guidelines. PI-SEC report 2.4. Regulatory and planning implications for municipalities [PDF]

open access: yes, 2019
Introduction. When engineering meets pragmatism, challenges arise in terms of how to solve problems. The process of studying how instruments and tools can be improved and developed to integrate energy aspects into urban planning, has from a ...
Nielsen, Brita Fladvad   +2 more
core  

La ciudad de pi

open access: yes, 2022
En este video se presenta una actividad lúdica utilizando los decimales del número irracional Pi, para representar la silueta de una ciudad.This video presents a playful activity using the decimals of the irrational number Pi, to represent the silhouette
Solís-Palma, Angie
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Observation of B --> K(+/-) pi(0) and B --> (K)0 pi(0), and evidence for B --> pi(+)pi(-).

open access: yes, 2000
We have studied charmless hadronic decays of B mesons into two-body final states with kaons and pions and observe three new processes with the following branching fractions: beta(B-->pi(+)pi(-)) = (4.3(+1.
Thorndike, EH   +49 more
core   +2 more sources

Determination of differential pencils with impulse from interior spectral data

open access: yesBoundary Value Problems, 2019
In this paper, we are concerned with the inverse spectral problems for differential pencils defined on [0,π] $[0,\pi ]$ with an interior discontinuity. We prove that two potential functions are determined uniquely by one spectrum and a set of values of ...
Yongxia Guo, Guangsheng Wei, Ruoxia Yao
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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