Results 161 to 170 of about 13,469,882 (326)
Detecting induced subgraphs [PDF]
An s-graph is a graph with two kinds of edges : subdivisible edges and real edges. A realisation of an s-graphB is any graph obtained by subdividing subdivisible edges of B into paths of arbitrary length (at least one).Benjamin Lévêque, David Y. Lin, Frédéric Maffray, Nicolas Trotignon +3 morecore Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman +17 morewiley +1 more sourceFeasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis +11 morewiley +1 more sourceThe neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal +8 morewiley +1 more sourceMeasurement of the ratios of branching fractions B(B(s)(0)-> D(s)(-)pi(+))/B(B(0)-> D(-)pi(+)) and B(B(+)->(D)over-bar(0)pi(+))/B(B(0)-> D(-)pi(+))
, 2006 We report an observation of the decay B(s)(0)-> D(s)(-)pi(+) in p (p) over bar collisions at root s = 1.96 TeV using 115 pb(-1) of data collected by the CDF II detector at the Fermilab Tevatron. We observe 83 +/- 11(stat) B(s)(0)-> D(s)(-)pi(+) candidates, representing a large increase in statistics over previous measurements and the first ...Abulencia, A, Acosta, D, Adelman, J, Affolder, T, Akimoto, T, Albrow, MG, Ambrose, D, Amerio, S, Amidei, D, Anastassov, A, Anikeev, K, Annovi, A, Antos, J, Aoki, M, Apollinari, G, Arguin, JF, Arisawa, T, Artikov, A, Ashmanskas, W, Attal, A, Azfar, F, Azzi-Bacchetta, P, Azzurri, P, Bacchetta, N, Bachacou, H, Badgett, W, Barbaro-Galtieri, A, Barnes, VE, Barnett, BA, Baroiant, S, Bartsch, V, Bauer, G, Bedeschi, F, Behari, S, Belforte, S, Bellettini, G, Bellinger, J, Belloni, A, Ben-Haim, E, Benjamin, D, Beretvas, A, Beringer, J, Berry, T, Bhatti, A, Binkley, M, Bisello, D, Bishai, M, Blair, RE, Blocker, C, Bloom, K, Blumenfeld, B, Bocci, A, Bodek, A, Boisvert, V, Bolla, G, Bolshov, A, Bortoletto, D, Boudreau, J, Bourov, S, Boveia, A, Brau, B, Bromberg, C, Brubaker, E, Budagov, J, Budd, HS, Budd, S, Burkett, K, Busetto, G, Bussey, P, Byrum, KL, Cabrera, S, Campanelli, M, Campbell, M, Canelli, F, Canepa, A, Carlsmith, D, Carosi, R, Carron, S, Casarsa, M, Castro, A, Catastini, P, Cauz, D, Cavalli-Sforza, M, Cerri, A, Cerrito, L, Chang, SH, Chapman, J, Chen, YC, Chertok, M, Chiarelli, G, Chlachidze, G, Chlebana, F, Cho, I, Cho, K, Chokheli, D, Chou, JP, Chu, PH, Chuang, SH, Chung, K, Chung, WH, Chung, YS, Ciljak, M, Ciobanu, CI, Ciocci, MA, Clark, A, Clark, D, Coca, M, Connolly, A, Convery, ME, Conway, J, Cooper, B, Copic, K, Cordelli, M, Cortiana, G, Cruz, A, Cuevas, J, Culbertson, R, Cyr, D, DaRonco, S, D'Auria, S, D'onofrio, M, Dagenhart, D, de Barbaro, P, De Cecco, S, Deisher, A, De Lentdecker, G, Dell'Orso, M, Demers, S, Demortier, L, Deng, J, Deninno, M, De Pedis, D, Derwent, PF, Dionisi, C, Dittmann, J, DiTuro, P, Dorr, C, Dominguez, A, Donati, S, Donega, M, Dong, P, Donini, J, Dorigo, T, Dube, S, Ebina, K, Efron, J, Ehlers, J, Erbacher, R, Errede, D, Errede, S, Eusebi, R, Fang, HC, Farrington, S, Fedorko, I, Fedorko, WT, Feild, RG, Feindt, M, Fernandez, JP, Field, R, Flanagan, G, Flores-Castillo, LR, Foland, A, Forrester, S, Foster, GW, Franklin, M, Freeman, JC, Fujii, Y, Furic, I, Gajjar, A, Gallinaro, M, Galyardt, J, Garcia, JE, Sciverez, MG, Garfinkel, AF, Gay, C, Gerberich, H, Gerchtein, E, Gerdes, D, Giagu, S, Giannetti, P, Gibson, A, Gibson, K, Ginsburg, C, Giolo, K, Giordani, M, Giunta, M, Giurgiu, G, Glagolev, V, Glenzinski, D, Gold, M, Goldschmidt, N, Goldstein, J, Gomez, G, Gomez-Ceballos, G, Goncharov, M, Gonzalez, O, Gorelov, I, Goshaw, AT, Gotra, Y, Goulianos, K, Latino, G +200 moreopenaire +13 more sourcesGlycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala +18 morewiley +1 more source