Results 111 to 120 of about 59,268 (267)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A Berezin-type map and a class of weighted composition operators

Concrete Operators, 2017
In this paper we consider the map L defined on the Bergman space La2(𝔺+)$L_a^2({{\rm\mathbb{C}}_{\rm{ + }}})$ of the right half plane ℂ+ by (Lf)(w)=πM′(w)∫𝔺+(fM′)(s)|bw(s)|2dA˜(s)$(Lf)(w) = \pi M'(w)\int\limits_{{{\rm\mathbb{C}}_{\rm{ + }}}} {\left( {{f \
Das Namita
doaj   +1 more source

Higher Readmissions at Safety-Net Hospitals and Potential Policy Solutions [PDF]

, 2012
The Hospital Readmissions Reduction Program (HRRP), established by the Affordable Care Act, ties a hospital's payments to its readmission rates -- with penalties for hospitals that exceed a national benchmark -- to encourage hospitals to reduce avoidable
Anthony Shih, Julia Berenson
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Genome Organization and Evolution of the AVR-Pita Avirulence Gene Family in the Magnaporthe grisea Species Complex

Molecular Plant-Microbe Interactions, 2008
The avirulence (AVR) gene AVR-Pita in Magnaporthe oryzae prevents the fungus from infecting rice cultivars containing the resistance gene Pi-ta. A survey of isolates of the M.
Chang Hyun Khang, Sook-Young Park, Yong-Hwan Lee, Barbara Valent, Seogchan Kang   +4 more
doaj   +1 more source

Incipient speciation in the rice blast fungus [PDF]

, 2015
Emerging fungal diseases of plants represent a growing issue accompanying global environmental changes, and there is tremendous interest in identifying the factors controlling their appearance and spread.
Adreit, Henri, Cros-Arteil, Sandrine, Fournier, Elisabeth, Gladieux, Pierre, Loos, Renaud, Milazzo, Joëlle, Ravel, Sébastien, Tharreau, Didier, Thierry, Maud   +8 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

DEVELOPMENT OF SYSTEMS OF MULTIPLEX PCR TO IDENTIFY GENES OF RESISTANCE TO MAGNAPORTHE GRISEA (HERBERT) BARR. AND SELECTION OF NEW RESISTANT FORMS (DONORS) ORYZA SATIVA L. TO PATHOGEN

Зерновое хозяйство России, 2018
Imperfect fungus Magnaporthe grisea is a phyto pathogen with a vast influence on most crops including rice. Economic damage of the disease is enormous in all rice cultivation zones of the world.
E. V. Dubina, P. I. Kostylev, L. V. Esaulova   +2 more
doaj   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source