Results 101 to 110 of about 59,268 (267)
RefDiff: Detecting Refactorings in Version Histories
, 2017 Refactoring is a well-known technique that is widely adopted by software engineers to improve the design and enable the evolution of a system. Knowing which refactoring operations were applied in a code change is a valuable information to understand ...
Silva, Danilo, Valente, Marco Tulio
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Characteristics of the extreme rainfall event and consequent flash floods in W Slovenia in September 2007 [PDF]
, 2009 During a weather front that passed over large parts of Slovenia on 18.9.2007, extreme rainfall events were triggered causing several severe flash floods with six casualties.
Kobold, Mira +2 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Health Challenges for the People of New Orleans: The Kaiser Post-Katrina Baseline Survey [PDF]
, 2007 Presents detailed findings from a household survey of Greater New Orleans area residents conducted in Fall 2006. Examines the health care status of residents and their access to health care services after the Hurricane Katrina ...
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Biotechnology & Biotechnological EquipmentHybridization was performed between the rice materials carrying the rice blast resistance genes Pi1, Pi2, and Pi-ta (R283) as the maternal parent and the broad compatibility restorer line R110 as the paternal parent.
Hailong Yang +8 more
doaj +1 more source