Results 81 to 90 of about 1,063,869 (264)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Implementation of a Feedback I2-Controlled Constant Temperature Environment Temperature Meter

open access: yesSensors, 2003
A feedback thermo-resistive sensor-based measurement scheme was proposed to estimate physical quantities like solar radiation (H), fluid velocity (U) and environment temperature (Ta).
Raimundo C. S. Freire   +6 more
doaj   +1 more source

Additional file 1 of In silico molecular and morphological analysis of rice blast resistant gene Pi-ta in Sri Lankan rice germplasm

open access: yes, 2021
Supplementary figure 1. The presence of resistant wPi-ta allele using the specific marker YL155/YL87. L: 100bp ladder, Lane 1: Positive control (Tetep), Lane 2: Negative control, Lane 3: Bg 360, Lane 4: At 362, Lane 5: Attakari,, Lane 6: Moddaikaruppan, Lane 7: Bg 358, Lane 8: Suwandal, Lane 9: Bw 372, Lane 10: Bg 406, Lane 11: Pachchaiperumal, Lane 12:
Terensan, Suvanthini   +5 more
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

BREEDING OF RICE VARIETIES WITH PYRAMIDING GENES TOLERANT TO DISEASES

open access: yesЗерновое хозяйство России, 2018
Rice can significantly decrease the harvest of grain when it’s damaged with a dangerous fungus ‘Pyricularia grisea’ (rice blast). Single genes resistant to the pathogen are usually unefficient. That’s why it’s necessary to breed productive rice varieties,
P. I. Kostylev   +4 more
doaj   +2 more sources

Additional file 3 of In silico molecular and morphological analysis of rice blast resistant gene Pi-ta in Sri Lankan rice germplasm

open access: yes, 2021
Supplementary table 2.
Terensan, Suvanthini   +5 more
openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Pcr-analysis of new rice varieties for the presence of blast resistance genes

open access: yesЗерновое хозяйство России
Rice is a basic food crop worldwide, but rice blast can cause significant yield losses, costing the global economy over $70 billion. Therefore, the development of new blast-resistant rice varieties is crucial.
P. I. Kostylev   +3 more
doaj   +1 more source

Genome-Wide Association of Rice Blast Disease Resistance and Yield-Related Components of Rice

open access: yesMolecular Plant-Microbe Interactions, 2015
Robust disease resistance may require an expenditure of energy that may limit crop yield potential. In the present study, a subset of a United States Department of Agriculture rice core collection consisting of 151 accessions was selected using a major ...
Xueyan Wang   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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