Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Intracoronary adjunctive therapies for ST-elevation myocardial infarction: a network meta-analysis of trials. [PDF]
Eur Heart J Cardiovasc PharmacotherLaborante R +14 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Политематический сетевой электронный научный журнал Кубанского государственного аграрного университета, 2011 The introgression of race-specific blast resistance genes Pi-ta, Pi-b, Pi-z into genotype of Russian rice variety has been performed by backcross method with marker control of donor alleles. Plants that demonstrated maximal similarity with recurrent parental form, the short vegetation period and abundant panicle fertility have been picked up from BC3 ...
openaire +1 more source
Association Between Calcaneal Inclination Angle and Spinal and Lower Limb Alignment: A Retrospective Radiographic Analysis. [PDF]
Diagnostics (Basel)Han Y +6 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Robust, Thermo-Malleable, and Closed-Loop Recyclable Mulberry Paper/Polyimine Composite Films Enabled by Dynamic Covalent Interpenetrating Networks. [PDF]
Materials (Basel)Liao Y +11 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
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Unlocking carrier confluence in covalent organic frameworks for efficient photoreduction of dilute nitrate to ammonia. [PDF]
Nat CommunSu Y, Wang Z, Deng X, Yin SF, Chen P.
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source