The unfolded protein response to PI*Z alpha‐1 antitrypsin in human hepatocellular and murine models [PDF]
Hepatology Communications, 2022 Alpha‐1 antitrypsin (AAT) deficiency (AATD) is an inherited disease caused by mutations in the serpin family A member 1 (SERPINA1, also known as AAT) gene.
Yuanqing Lu +9 more
doaj +2 more sources
Alpha-1 antitrypsin Pi∗Z allele is an independent risk factor for liver transplantation and death in patients with advanced chronic liver disease [PDF]
JHEP Reports, 2022 Background & Aims: Alpha-1 antitrypsin (AAT) deficiency causes/predisposes individuals to advanced chronic liver disease (ACLD). However, the role of the SERPINA1 Pi∗Z allele in patients who have already progressed to ACLD is unclear.
Lorenz Balcar +16 more
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Berberine potentiates liver inflammation and fibrosis in the PI*Z hAAT transgenic murine model. [PDF]
PLoS ONEBackgroundAlpha-1 antitrypsin deficiency (AATD) is an inherited disease, the common variant caused by a Pi*Z mutation in the SERPINA1 gene. Pi*Z AAT increases the risk of pulmonary emphysema and liver disease.
Yuanqing Lu +5 more
doaj +2 more sources
Mild Iron Overload as Seen in Individuals Homozygous for the Alpha-1 Antitrypsin Pi*Z Variant Does Not Promote Liver Fibrogenesis in HFE Knockout Mice [PDF]
Cells, 2019 The presence of the homozygous ‘Pi*Z’ variant of alpha-1 antitrypsin (AAT) (‘Pi*ZZ’ genotype) predisposes to liver fibrosis development, but the role of iron metabolism in this process remains unknown.
Nurdan Guldiken +8 more
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Alpha-1 antitrypsin Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide: an update [PDF]
International Journal of COPD, 2017 Ignacio Blanco,1 Patricia Bueno,2 Isidro Diego,3 Sergio Pérez-Holanda,4 Francisco Casas-Maldonado,5 Cristina Esquinas,6 Marc Miravitlles6,7 1Alpha1-Antitrypsin Deficiency Spanish Registry (REDAAT), Fundación Respira, Spanish Society of ...
Blanco I +6 more
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Assessment of the impact of Z-Spring appliances and clear aligners on salivary parameters and periodontal health in children: a randomized clinical trial [PDF]
BMC Oral HealthBackground Removable appliances greatly affect oral hygiene and increase the amount of plaque retention. The aim of this prospective study was to evaluate the effects of anterior crossbite treatment with Z-spring appliance and clear aligners on ...
İrem Kapici +2 more
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Integral representation of vertical operators on the Bergman space over the upper half-plane
Comptes Rendus. Mathématique, 2023 Let $\Pi $ denote the upper half-plane. In this article, we prove that every vertical operator on the Bergman space $\mathcal{A}^2(\Pi )$ over the upper half-plane can be uniquely represented as an integral operator of the form \begin{equation*} \left ...
Bais, Shubham R. +2 more
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Double exotic state productions in pion and kaon induced reactions
European Physical Journal C: Particles and Fields, 2021 In the present work, we investigate the pion/kaon induced $$P_c/P_{cs}$$ P c / P cs productions with $$Z_c$$ Z c state off proton target with an effective Lagrangian approach.
Jing Liu, Dian-Yong Chen, Jun He
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Pionic transitions from $$Z_c(4020)$$ Z c ( 4020 ) to D wave charmonia
European Physical Journal C: Particles and Fields, 2023 In the present work, we investigate the charmed meson loops contributions to the pionic transitions from $$Z_c(4020)^+$$ Z c ( 4020 ) + to the D wave triplets charmonia by using an effective Lagrangian approach.
Xiao-Yu Qi, Qi Wu, Dian-Yong Chen
doaj +1 more source
A quantitative subspace Balian-Low theorem
, 2021 Let $\mathcal G\subset L^2(\mathbb R)$ be the subspace spanned by a Gabor Riesz sequence $(g,\Lambda)$ with $g\in L^2(\mathbb R)$ and a lattice $\Lambda\subset\mathbb R^2$ of rational density.
Caragea, Andrei +3 more
core +1 more source