Results 221 to 230 of about 3,793,930 (259)

Genomic resources to advance seed coat color and patterning genetics and breeding in common bean (Phaseolus vulgaris L.). [PDF]

Plant Genome
Roy J, Lee R, Osborne C, Miklas PN, Osorno JM, McClean PE.   +5 more
europepmc   +1 more source

Design, synthesis, and biological evaluation of quinolin-2-one/thiazole hybrids as multi-targeted antiproliferative agents inducing caspase-dependent apoptosis. [PDF]

Sci Rep
Al-Wahaibi LH, Alzahrani AYA, Bräse S, Tawfeek HN, Youssif BGM.   +4 more
europepmc   +1 more source

Association of Fetal Cerebrovascular Resistance and Neurodevelopment in Congenital Heart Disease: A Physiology-Based Analysis. [PDF]

Prenat Diagn
Bradford VR, Lipsitz SR, Pujols KH, Waring K, Sadhwani A, Tworetzky W, Newburger JW, Friedman KG, Rollins CK.   +8 more
europepmc   +1 more source

Effects of concurrent neuropathologies with Alzheimer disease neuropathologic change on cognitive decline: Minimal impact of vascular brain injury compared with other combinations. [PDF]

J Neuropathol Exp Neurol
Yasuda SM, Mock C, Gauthreaux K, Chan KCG, Keene CD, Culhane JE, Chen YC, Kukull W.   +7 more
europepmc   +1 more source

Microfluidic Cytotongue system enables early, label-free detection of CAR-T-induced mechanical softening in tumor spheroids. [PDF]

Microsyst Nanoeng
Kim S, Seo GM, Bae J, Noort DV, Park S.
europepmc   +1 more source

Community-Based <i>SERPINA1</i> Genotyping in an Isolated Alpine Town Reveals Heterozygous Pi*Mheerlen Carriers: Implications for Targeted Screening. [PDF]

Biomedicines
Ragnoli B, Bertelegni C, Veselagu X, Chiazza F, Malerba M.   +4 more
europepmc   +1 more source

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Pi-Z Phenotypes in a Pulmonary Clinic: Their Prevalence and Physiologic State

American Journal of Clinical Pathology, 1978
A series of 1,458 consecutive patients referred to the Cleveland Veterans Administration Pulmonary Clinic for pulmonary function studies was evaluated for alpha 1-antitrypsin deficiency by determination of serum trypsin inhibitory capacity (STIC). Protease inhibitor (Pi) phenotyping was performed on all sera with STIC values less than 1.6 mg/ml.
A A, Gerblich, J, Kleinerman, D J, Rynbrandt, E H, Chester, J, Ihrig   +4 more
openaire   +2 more sources

Occupational Exposure Risks in Individuals with PI*Z α1-Antitrypsin Deficiency

American Journal of Respiratory and Critical Care Medicine, 2000
Abstract We obtained questionnaire and spirometry data from 128 α1-antitrypsin (α1AT)-deficient individuals with phenotype PI*Z to examine the relationship between chronic respiratory symptoms, airflow limitation, treatment requirements, and semiquantitative estimates of occupational exposure to dust, fumes, smoke, and gas.
A S, Mayer, J K, Stoller, B, Bucher Bartelson, A, James Ruttenber, R A, Sandhaus, L S, Newman   +5 more
openaire   +2 more sources

An Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Circulating Pi*Z Alpha1-Antitrypsin Polymers

2023
Enzyme-linked immunosorbent assay (ELISA) is a sensitive immunoassay based on specific antigen-antibody reaction that is used for quantitative/qualitative analysis of various analytes in serum, plasma, saliva, cell and tissue lysates, and urine. ELISAs are typically performed in multi-well plates and depending on the design require coating antibody ...
Sabina, Janciauskiene, Tobias, Welte, Matthias, Lehmann   +2 more
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Age of SERPINA1 Gene PI Z Mutation: Swedish and Latvian Population Analysis

Annals of Human Genetics, 2008
SummaryAlpha 1‐antitrypsin (A1AT) deficiency, one of the most common inborn errors of metabolism in Caucasians, is characterized by a low serum concentration of A1AT and a high risk of pulmonary emphysema and liver disease. The allelic frequency for the most common protease inhibitor (PI) Z mutation in the SERPINA1 gene is 2–5% in Caucasians of ...
B, Lace, T, Sveger, A, Krams, G, Cernevska, A, Krumina   +4 more
openaire   +2 more sources