Results 111 to 120 of about 4,298,011 (325)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner +4 morewiley +1 more sourcePerfil sociodemográfico y clínico de las mujeres con síndrome hellp
Revista de Enfermagem da Universidade Federal de Santa Maria, 2017 Objective: to describe the sociodemographic and clinical women with HELLP. Method: descriptive, quantitative approach of retrospective consists of all 52 records of women with HELLP syndrome from 2008 to 2012.José Francisco Ribeiro, Maria do Socorro de Almeida Chaves Soares, Cleidiomar Oliveira Rodrigues, Vanessa Oliveira Rodrigues Bezerra, Kleiton Richard da Silva Araújo +4 moredoaj +1 more sourcePotential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk +4 morewiley +1 more sourceEffective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet +17 morewiley +1 more sourceDalitz Plot Analysis of B+- --> pi+-pi+-pi-+ Decays
, 2009 Comment: 16 pages, 8 postscript figures, published in Phys.B. Aubert, R. Barate, D. Boutigny, F. Couderc, Y. Karyotakis, J. P. Lees, V. Poireau, V. Tisserand, A. Zghiche, E. Grauges, A. Palano, M. Pappagallo, A. Pompili, J. C. Chen, N. D. Qi, G. Rong, P. Wang, Y. S. Zhu, G. Eigen, I. Ofte, B. Stugu, G. S. Abrams, M. Battaglia, A. B. Breon, D. N. Brown, J. Button Shafer, R. N. Cahn, M. S. Gill, A. V. Gritsan, Y. Groysman, R. G. Jacobsen, J. Kadyk, L. T. Kerth, Y.u. G. Kolomensky, G. Kukartsev, G. Lynch, L. M. Mir, P. J. Oddone, T. J. Orimoto, N. A. Roe, M. T. Ronan, W. A. Wenzel, M. Barrett, K. E. Ford, T. J. Harrison, A. J. Hart, C. M. Hawkes, B. Lewandowski, M. Pelizaeus, K. Peters, T. Schroeder, T. Cuhadar Donszelmann, B. G. Fulsom, C. Hearty, N. S. Knecht, T. S. Mattison, J. A. McKenna, A. Khan, P. Kyberd, M. Saleem, L. Teodorescu, A. E. Blinov, V. E. Blinov, A. D. Bukin, V. P. Druzhinin, V. B. Golubev, E. A. Kravchenko, A. P. Onuchin, S. I. Serednyakov, Y. I. Skovpen, E. P. Solodov, D. Best, M. Bondioli, M. Bruinsma, M. Chao, I. Eschrich, D. Kirkby, A. J. Lankford, M. Mandelkern, B. L. Hartfiel, S. D. Foulkes, J. W. Gary, O. Long, B. C. Shen, K. Wang, L. Zhang, D. del Re, H. K. Hadavand, E. J. Hill, D. B. MacFarlane, H. P. Paar, J. W. Berryhill, C. Campagnari, A. Cunha, M. A. Mazur, J. D. Richman, W. Verkerke, T. W. Beck, A. M. Eisner, C. J. Flacco, C. A. Heusch, J. Kroseberg, W. S. Lockman, G. Nesom, T. Schalk, B. A. Schumm, A. Seiden, P. Spradlin, D. C. Williams, M. G. Wilson, J. Albert, G. P. Dubois Felsmann, A. Dvoretskii, D. G. Hitlin, I. Narsky, T. Piatenko, F. C. Porter, A. Ryd, A. Samuel, R. Andreassen, S. Jayatilleke, G. Mancinelli, B. T. Meadows, M. D. Sokoloff, F. Blanc, P. Bloom, S. Chen, W. T. Ford, U. Nauenberg, A. Olivas, P. Rankin, W. O. Ruddick, J. G. Smith, K. A. Ulmer, S. R. Wagner, J. Zhang, A. Chen, E. A. Eckhart, A. Soffer, W. H. Toki, R. J. Wilson, Q. Zeng, D. Altenburg, E. Feltresi, A. Hauke, B. Spaan, T. Brandt, J. Brose, H. M. Lacker, R. Nogowski, S. Otto, A. Petzold, G. Schott, J. Schubert, K. R. Schubert, R. Schwierz, J. E. Sundermann, D. Bernard, G. R. Bonneaud, C. Thiebaux, G. Vasileiadis, M. Verderi, D. J. Bard, P. J. Clark, W. Gradl, F. Muheim, S. Playfer, Y. Xie, M. Andreotti, V. Azzolini, D. Bettoni, C. Bozzi, R. Calabrese, G. Cibinetto, E. Luppi, M. Negrini, L. Piemontese, F. Anulli, R. Baldini Ferroli, A. Calcaterra, R. de Sangro, G. Finocchiaro, P. Patteri, I. M. Peruzzi, M. Piccolo, A. Zallo, A. Buzzo, R. Capra, R. Contri, M. Lo Vetere, M. Macri, M. R. Monge, S. Passaggio, C. Patrignani, E. Robutti, A. Santroni, S. Tosi, S. Bailey, E. Won, J. Wu, N. Arnaud, F. Di Lodovico, P. S. Jackson, G. D. Lafferty, C. Chen, C. Dallapiccola, F. Palombo, C. Sciacca, G. Raven, J. Strube, J. Ocariz, G. Calderini, M. Carpinelli, G. Marchiori, N. Neri, C. Voena, T. Adye, G. Hamel de Monchenault, G. Vasseur, D. Su, M. Bomben, L. Lanceri, S. Banerjee, R. Kowalewski, J. M. Roney, T. E. Latham, S. L. Wu +226 moreopenaire +5 more sourcesMonitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien +35 morewiley +1 more source