Results 121 to 130 of about 4,298,011 (325)
Introduction: Guided tissue regeneration using bone grafts and barrier membranes has shown success, but newer materials like mineral trioxide aggregate (MTA) may enhance outcomes.
Pratiksha Neminath Patil +5 more
doaj +1 more source
Study of the $\pi^+\pi^-$ System in $\pi^-\pi^+\pi^-$ Final States at COMPASS [PDF]
The C OMPASS experiment located at CERN’s Super Proton Synchrotron is a multi-purpose fixed- target spectrometer aimed at studying the structure and spectrum of light hadrons using muon and hadron beams on various targets. With its high acceptance and resolution, it has e.g.
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Amplitude Analysis of B -> pi pi pi and B -> K pi pi
We present preliminary results of a maximum-likelihood Dalitz-plot analysis of the charmless hadronic B decays to the final states pi pi pi and K pi pi from data corresponding to an integrated on-resonance luminosity of 166 fb^-1 recorded by the BABAR experiment at the SLAC PEP-II asymmetric-energy B Factory.
Aubert, B., Collaboration, BABAR
openaire +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
nnU-Net weights for Prostate segmentation used in PI-CAI Challenge - Phase 1
Noëlie Debs +6 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Incentives for Better Performance in Health Care
Incentives for better performance in health care have several modes and methods. They are designed to motivate and encourage people to perform well and improve their outcomes.
Asaad Abduljawad, Assaf F. Al-Assaf
doaj

