Results 111 to 120 of about 2,239,859 (281)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Design and Simulation of an LQR-PI Control Algorithm for Medium Wind Turbine
Energies, 2019 In this paper, a new linear quadratic regulator (LQR) and proportional integral (PI) hybrid control algorithm for a permanent-magnet synchronous-generator (PMSG) horizontal-axis wind turbine was developed and simulated. The new algorithm incorporates LQR
Kwansu Kim +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Research on Current Drive System of Magnetorheological Damper Based on Fuzzy PI Control. [PDF]
Materials (Basel), 2022 Li W, Liang H, Xia D, Fu J, Luo L, Yu M.
europepmc +1 more source
Implications of genotype and amino acid sup-ply on pork quality [PDF]
, 2006 An experiment was conducted to evaluate the effect of different feeding regimes and genotypes on growth performance, carcass characteristics, composition and eating quality of pork under organic framework conditions.
Acosta Aragon, Dr. Yunior +5 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
A PI Control Method with HGSO Parameter Regulator for Trajectory Planning of 9-DOF Redundant Manipulator. [PDF]
Sensors (Basel), 2022 Liu M, Liu T, Zhu M, Chen L.
europepmc +1 more source
, 1999 Time delays reduces the performance of any controlled system. If neglected in the design phase, the system may even become unstable when using the designed controller.
Blom, Jonas +2 more
core +1 more source