Results 121 to 130 of about 231,101 (299)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Bland-Altman plots with PI ≤1 and PI ≤1.
, 2019 Bland-Altman plot for systolic arterial pressure with PI ≤1 (A), systolic arterial pressure with PI >1 (B), diastolic arterial pressure with PI ≤1 (C), diastolic arterial pressure with PI >1 (D), mean arterial pressure with PI ≤1 (E), and mean arterial ...
Masahiro Takaya (4785021) +6 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 2019 Gestational age (GA)-specific longitudinal reference centiles for middle cerebral artery pulsatility index (MCA-PI).
Maria Angela Rustico (8098529) +7 more
core +1 more source
Asian Journal of Medical SciencesBackground: Accurate anesthesia depth monitoring is crucial for patient safety. Bispectral index (BIS) measures brain activity, whereas perfusion index (PI) reflects peripheral blood flow and sympathetic tone.
Karthik Raj M +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Significance test (*p < 0.05) of pollution index (PI) difference among different land use types.
, 2016 Significance test (*p < 0.05) of pollution index (PI) difference among different land use types.
Ranhao Sun (2736073) +1 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Campbell, Mr Ruben Mrs Marion, Manila Pi
, 2017 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Australian Red Cross Society, National Office
core
, 2019 Gestational age (GA)-specific longitudinal reference centiles for umbilical artery pulsatility index (UA-PI).
Maria Angela Rustico (8098529) +7 more
core +1 more source