Results 41 to 50 of about 103,320 (266)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Integration of the Barcelona Supercomputing Center for CMS computing: Towards large scale production [PDF]

EPJ Web of Conferences
The CMS experiment is working to integrate an increasing number of High Performance Computing (HPC) resources into its distributed computing infrastructure.
Acosta-Silva C., Delgado Peris A., Flix Molina J., Hernández J.M., Pérez-Calero Yzquierdo A., Pineda Sánchez E., Villalonga Domínguez I.   +6 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Effect of pooled tracheal sample testing on the probability of Mycoplasma hyopneumoniae detection

Scientific Reports
Tracheal pooling for Mycoplasma hyopneumoniae (M. hyopneumoniae) DNA detection allows for decreased diagnostic cost, one of the main constraints in surveillance programs.
Ana Paula Serafini Poeta Silva, Robert Mugabi, Marisa L. Rotolo, Seth Krantz, Dapeng Hu, Rebecca Robbins, Deanne Hemker, Andres Diaz, A. W. Tucker, Rodger Main, Jean Paul Cano, Perry Harms, Chong Wang, Maria Jose Clavijo   +13 more
doaj   +1 more source

The effects of PRRS on the environmental impact of pig production: a life cycle assessment study

Frontiers in Veterinary Science
The Porcine Reproductive and Respiratory Syndrome (PRRS) is a viral pig disease that increases mortality rates and reduces (re)production performance.
Greg J. Thoma, Lucina Galina Pantoja, Daniel C. L. Linhares, Ana Paula Serafini Poeta Silva, Lindsay Case, Pieter W. Knap   +5 more
doaj   +1 more source

Comparative analysis of Machine Learning-based eviction techniques and LRU mechanisms for CMS data caching [PDF]

EPJ Web of Conferences
The Large Hadron Collider (LHC) at CERN in Geneva is preparing for a major upgrade that will improve both its accelerator and particle detectors. This strategic move comes in anticipation of a tenfold increase in proton-proton collisions, expected to ...
Delgado Peris A., Flix Molina J., Hernández J.M., Pérez-Calero Yzquierd A., Rodríguez Calonge F.J., Serrano P., Sikora A., Vilalta J.   +7 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Autonomous Underwater Navigation and Optical Mapping in Unknown Natural Environments

Sensors, 2016
We present an approach for navigating in unknown environments while, simultaneously, gathering information for inspecting underwater structures using an autonomous underwater vehicle (AUV).
Juan David Hernández, Klemen Istenič, Nuno Gracias, Narcís Palomeras, Ricard Campos, Eduard Vidal, Rafael García, Marc Carreras   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Deficiências nutricionais e suplementação em indivíduos submetidos à gastroplastia redutora do tipo Y de Roux

Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 2017
Introdução: A obesidade é uma doença crônica multifatorial, que promove comorbidades importantes desencadeando grande repercussão à saúde. Porém, quando instalada e diante do insucesso de formas conservadoras de tratamento, a gastroplastia é indicada ...
Dora Castro Agulhon Segura, Simone Daiane Wozniak, Franciele Luz de Andrade, Thais Marta Marreto, Edimar Dal Ponte   +4 more
doaj