Results 41 to 50 of about 565,619 (298)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Laser-plasma interactions with a Fourier-Bessel Particle-in-Cell method

open access: yes, 2015
A new spectral particle-in-cell (PIC) method for plasma modeling is presented and discussed. In the proposed scheme, the Fourier-Bessel transform is used to translate the Maxwell equations to the quasi-cylindrical spectral domain.
Agustin Lifschitz   +7 more
core   +2 more sources

Detailed particle-in-cell simulations on the transport of a relativistic electron beam in plasmas [PDF]

open access: yes, 2009
We present comprehensive two-dimensional (2D) particle-in-cell (PIC) simulations on the transport of a relativistic electron beam in a plasma in the context of fast ignition fusion.
Karmakar, Anupam   +4 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Incidência bacteriana e perfil de resistência a antimicrobianos em pacientes pediátricos de um hospital público de Rondônia, Brasil

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2013
As infecções de maiores preocupações dos profissionais da área de saúde são as que ocorrem nas unidades que atendem pacientes mais suscetíveis à infecção - Pediatria, Unidades de Terapia Intensiva (UTI) e Unidades Oncológicas.
Vinicius Tadeu Ramos da Silva Grillo   +4 more
doaj  

Voevodsky's mixed motives versus Kontsevich's noncommutative mixed motives [PDF]

open access: yes, 2014
Following an insight of Kontsevich, we prove that the quotient of Voevodsky's category of geometric mixed motives DM by the endofunctor -Q(1)[2] embeds fully-faithfully into Kontsevich's category of noncommutative mixed motives KMM.
Tabuada, Goncalo
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The effects of PRRS on the environmental impact of pig production: a life cycle assessment study

open access: yesFrontiers in Veterinary Science
The Porcine Reproductive and Respiratory Syndrome (PRRS) is a viral pig disease that increases mortality rates and reduces (re)production performance.
Greg J. Thoma   +5 more
doaj   +1 more source

Pigs’ aggressive temperament affects pre-slaughter mixing aggression, stress and meat quality

open access: yesAnimal, 2010
Pre-slaughter stress has a negative impact on animal welfare and on meat quality. Aggressive behaviour when pigs are mixed together for transportation to, or on arrival at, the abattoir is an important factor in pre-slaughter stress.
R.B. D’Eath   +12 more
doaj   +1 more source

Development of a low-alpha-emitting {\mu}-PIC for NEWAGE direction-sensitive dark-matter search

open access: yes, 2017
NEWAGE is a direction-sensitive dark-matter-search experiment that uses a micro-patterned gaseous detector, or {\mu}-PIC, as the readout. The main background sources are {\alpha}-rays from radioactive contaminants in the {\mu}-PIC.
Hashimoto, Takashi   +9 more
core   +1 more source

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