Results 51 to 60 of about 116,173 (293)

Assessment of Genetic Diversity among Pigeon pea Male Sterile lines and Popular Cultivars using SSR Markers

Electronic Journal of Plant Breeding, 2016
In the present study genetic diversity studies have been carried out using twenty five SSR markers in a set of pigeonpea genotypes comprising of male sterile lines and popular cultivars. The primers amplified a total of 99 bands with highest PIC of 0.79.
SNCVL Pushpavalli, R. Raja Rajeswari and, C.V. Sameer Kumar   +2 more
doaj   +1 more source

ERK 1/2 Activation Mediates the Neuroprotective Effect of BpV(pic) in Focal Cerebral Ischemia–Reperfusion Injury

Neurochemical Research, 2018
Bisperoxovanadium (pyridine-2-carboxyl) [bpV(pic)] is a commercially available PTEN inhibitor. Previous studies from us and others have shown that bpV(pic) confers neuroprotection in cerebral ischemia injury.
Rui Liu, Junchun Tang, Meng-Xian Pan, Zhuang Yang, Ya Zhang, Huabao Liao, Dan Zhao, Y. Lei, Rui-Xue Lei, Shu Wang, An-Chun Liu, Xingping Qin, Juan Chen, Zhi-feng Zhang, Qi Wan   +14 more
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Genetic and phenotypic time trends of litter size, piglet mortality, and birth weight in pigs

Frontiers in Animal Science, 2023
IntroductionLitter size in pigs has increased steadily since 1990. Because of unfavorable genetic correlations with piglet mortality, breeding goals should include survival traits next to litter size.
Pieter W. Knap, Egbert F. Knol, A. Christian Sørensen, Abe E. Huisman, Dianne van der Spek, Louisa J. Zak, Ana Granados Chapatte, Craig R. G. Lewis   +7 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Structure of promoter-bound TFIID and insight into human PIC assembly

Nature, 2016
The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II (Pol II)-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter.
R. Louder, Yuan He, J. López-Blanco, Jie Fang, P. Chacón, E. Nogales   +5 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Applying novel economic simple green sample preparation procedures on natural and industrial specimens for chromatographic determination of insecticidal residues

Scientific Reports, 2023
Spraying a tertiary blend of the insecticides (hexythiazox, imidacloprid, and thiamethoxam), on tomato fruits, is a routine in agriculture-attentive countries.
Amira M. Hegazy, Hamada M. Mahmoud, Mohamed A. Elsayed, Nouruddin W. Ali, Rehab M. Abdelfatah   +4 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Estimating genetic parameters of digital behavior traits and their relationship with production traits in purebred pigs

Genetics Selection Evolution
Background With the introduction of digital phenotyping and high-throughput data, traits that were previously difficult or impossible to measure directly have become easily accessible, offering the opportunity to enhance the efficiency and rate of ...
Mary Kate Hollifield, Ching-Yi Chen, Eric Psota, Justin Holl, Daniela Lourenco, Ignacy Misztal   +5 more
doaj   +1 more source