Results 41 to 50 of about 3,143 (223)
The Effect of Slot-Code Optimization on Travel Times in Common Unit-Load Warehouses [PDF]
, 2013 The main aim of this paper is to estimate material handling times reductions in one-block unit-load warehouse organised with an optimal slot-code allocation, rather than with a uniform pick/store locations distribution, while comparing single and dual ...
Fumi, A, Scarabotti, L, Schiraldi, Mm
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Design and Control of Warehouse Order Picking: a literature review [PDF]
, 2006 Order picking has long been identified as the most labour-intensive and costly activity for almost every warehouse; the cost of order picking is estimated to be as much as 55% of the total warehouse operating expense.
Koster, M.B.M. (René) de +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Perbaikan Produktivitas Picking Order dengan Metode Routing Heuristic di Gudang Pusat Suku Cadang Otomotif [PDF]
, 2018 Order picking is a process to fulfill customer order, with fast timing and provide high customer satisfaction. The order picking process is the highest cost in both manual and automatic systems, so it is necessary to improve efficiency and productivity ...
Kusumah, L. H. (Lien) +1 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Determining Number of Zones in a Pick-and-pack Orderpicking System [PDF]
, 2005 In this study we consider a pick-to-pack orderpicking system, in which batches of orders are picked simultaneously from different(work) zones by a group of order pickers.
Koster, M.B.M. (René) de +1 more
core
Robotized Warehouse Systems: Developments and Research Opportunities [PDF]
, 2017 Robotized handling systems are increasingly applied in distribution centers. They require little space, provide flexibility in managing varying demand requirements, and are able to work 24/7.
Azadeh, K. (Kaveh) +2 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source