Results 91 to 100 of about 109,408 (264)

Electrically driven cation exchange for in situ fabrication of individual nanostructures

open access: yesNature Communications, 2017
Cation exchange, traditionally driven by ion solvation or thermal activation, is a robust approach for preparing heterogeneous nanostructures but lacks selectivity for preparation of individual nanocrystals.
Qiubo Zhang   +12 more
doaj   +1 more source

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

open access: yesAdvanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld   +5 more
wiley   +1 more source

Prevalence of secondary arterial hypertension in patients with acute renal failure in a secondary-level pediatric hospital in Northwestern Mexico

open access: yesBoletín Médico del Hospital Infantil de México
Background: The worldwide prevalence of arterial hypertension in pediatric patients is 3.5%, and it has repercussions at renal, cardiovascular, neurological, and lifestyle levels.
Humberto Peña-Guevara   +2 more
doaj   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

Interfacial Fluorinated Ion Crowding Enables Reversible Zinc Metal Batteries

open access: yesAngewandte Chemie, EarlyView.
Unlike conventional single‐anion electrolytes with limited interfacial regulation, interfacial F‐ion crowding enables dense occupation of the inner Helmholtz plane through cooperative fluorinated anions, thereby generating a fluorine‐rich interface that excludes water, homogenizes Zn2+ nucleation, promotes Zn (100)‐oriented deposition, and enables ...
Xinyu Zhang   +18 more
wiley   +2 more sources

Size-Effect-Based Dimension Compensations in Wet Etching for Micromachined Quartz Crystal Microstructures

open access: yesMicromachines
Microfabrication technology with quartz crystals is gaining importance as the miniaturization of quartz MEMS devices is essential to ensure the development of portable and wearable electronics.
Yide Dong   +6 more
doaj   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu   +13 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä   +18 more
wiley   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

Estrategia de Medición, Evaluación y Mejora Continua de Calidad

open access: yesTecnología y Ciencia, 2019
La medición permite obtener datos al cuantificar atributos de un ente usando métricas. Para obtener información de estos datos la evaluación interpreta las medidas obtenidas usando indicadores.
Belén Rivera, Pablo Becker, Luis Olsina
doaj  

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