Results 211 to 220 of about 5,057,050 (249)
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Role of zinc in blockade of excitotoxic action of quinolinic acid by picolinic acid
Amino Acids, 1998This study examined whether picolinic acid (PIC) inhibits quinolinic acid (QUIN)-induced excitotoxicity through zinc chelation. Injection of QUIN into the nucleus basalis magnocellularis significantly depleted cortical choline acetyltransferase activity 7 days post injection and PIC inhibited this response. Zinc augmented the QUIN- but not NMDA-induced
Richard J. Beninger +3 more
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Macrophage Activating Properties of The Tryptophan Catabolite Picolinic Acid
2003Recent studies have suggested a role for aminoacid catabolites as important regulators of macrophage (Mphi) activities. We reported previously that picolinic acid (PA), a tryptophan catabolite produced under inflammatory conditions and a costimulus with IFNgamma of Mphi effector functions, is a selective inducer of the Mphi inflammatory protein-1alpha (
Annamaria Rapisarda +5 more
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Influence of Dietary Picolinic Acid on Mineral Metabolism in the Rat
Annals of Nutrition and Metabolism, 1988Male rats were fed isonitrogenous, isocaloric diets containing different amounts of dietary zinc and picolinic acid (PA) (25, 60, 120 ppm Zn, 0, 20, 40, 60 mmol PA/kg diet) and balance collections of urine and faeces made over a 4-day period. Rats fed 25 ppm Zn were in negative Zn and Cu balance during the experiment.
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Zinc Absorption in Cattle with a Dietary Picolinic Acid Supplement
The Journal of Nutrition, 1981The effect of picolinic acid and hydroxyquinolines in intestinal zinc absorption of cattle was studied. In contrast to reports of the absorption in rat and in man, picolinic acid did not enhance zinc absorption in cattle. In two calves suffering from Adema disease, the bovine parallel to Acrodermatitis enteropathica, hydroxyquinoline supplementation ...
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Journal of Radioanalytical and Nuclear Chemistry, 2012
N. Evans +3 more
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N. Evans +3 more
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