Results 111 to 120 of about 21,155 (219)

The Antimuscarinic Agent Tolterodine Regulates Bladder Extracellular Matrix in Partial Bladder Outlet Obstruction in Rats

Cellular Physiology and Biochemistry, 2018
Background/Aims: Antimuscarinic agents can delay the progression of bladder dysfunction caused by bladder outlet obstruction (BOO). To date, the relationship between muscarinic receptor activity and the bladder extracellular matrix (ECM) remains unclear.
Tong-Xin Yang, De-Yi Luo, Yi-Fei Lin, Qiang Liu, Xiang Cai, Jian-Zhong Ai, Hong Li, Hong Shen, Kun-Jie Wang   +8 more
doaj   +1 more source

Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury. [PDF]

, 2019
Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocardial function, yet exact mechanisms remain unclear. Impaired autophagy leads to heart failure and mitophagy is important for mitigating ischemia/reperfusion injury ...
Andres, Allen M, Crupi, Annunziata, Czer, Lawrence S, Esmailian, Fardad, Gottlieb, Roberta A, Hou, Jean, Marek-Iannucci, Stefanie, Mentzer, Robert M, Sin, Jon, Taylor, David J, Thomas, Amandine   +10 more
core  

Modulation of extracellular matrix by nutritional hepatotrophic factors in thioacetamide-induced liver cirrhosis in the rat [PDF]

, 2009
Nutritional substances associated to some hormones enhance liver regeneration when injected intraperitoneally, being denominated hepatotrophic factors (HF).
ALOIA, T.P.A., AVANZO, J.L., BATEMAN, A., DAGLI, M.L.Z., GUERRA, R.R., HERNANDEZ-BLAZQUEZ, F.J., PARRA, O.M., TROTTA, M.R.   +7 more
core   +2 more sources

N‐Acetylcysteine Reduces Alveolar Bone Loss and Mitigates Systemic Oxidative Damage in Rats With Apical Periodontitis

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study aimed to evaluate the effects of N‐acetylcysteine (NAC) supplementation in apical periodontitis (AP) induced in rats. Methodology Eighteen male Wistar rats were randomly assigned to three groups: control, AP, and AP plus NAC.
Ian Wesley Rocha dos Santos, Deiweson Souza‐Monteiro, Deborah Ribeiro Frazão, Zuleni Alexandre Lisboa da Silva, João Daniel Mendonça de Moura, Jorddy Neves Cruz, Fabrício Mezzomo Collares, Renata Duarte de Souza‐Rodrigues, Luciano Tavares Ângelo Cintra, Rafael Rodrigues Lima   +9 more
wiley   +1 more source

Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease

Journal of Anatomy, EarlyView.
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit, Denisa Belisova, Zuzana Sumbalova Koledova, Neal Anthwal, Abigail S. Tucker   +4 more
wiley   +1 more source

Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects

, 2020
Arterial tortuosity syndrome (ATS) is a recessively inherited connective tissue disorder, mainly characterized by tortuosity and aneurysm formation of the major arteries.
Barnhoorn, Sander, Beyens, Aude, Boel, Annekatrien, Burger, Joyce, Callewaert, Bert, Casteleyn, Christophe, Coucke, Paul, Descamps, Benedicte, Essers, Jeroen, Reinhardt, Dieter, Renard, Marjolijn, van der Pluijm, Ingrid, Vanhomwegen, Marine, Vanhove, Christian, Willaert, Andy   +14 more
core   +1 more source

Effects of low-intensity pulsed ultrasound on injured skeletal muscle [PDF]

, 2013
BACKGROUND:Low-intensity pulsed ultrasound (LIPUS) has been shown to stimulate tissue metabolism and accelerate muscle healing. However, the optimal parameters in the use of LIPUS are still not clear.OBJECTIVE:The aim of this study was to analyze the ...
Fernandes, Kelly Rossetti, Montalti, Camila Stein, Renno, Ana Claudia Muniz, Rodrigues, Natália C., Souza, Natália V. C. K. L., Toma, Renata Luri   +5 more
core   +4 more sources

Is the temporomandibular joint affected by rheumatoid arthritis? A comparative investigation with knee arthritis in an experimental rat model

Journal of Anatomy, EarlyView.
Animals were sensitized with mBSA emulsified in CFA/IFA and subsequently received three intra‐articular injections of mBSA into either the TMJ or the knee (once per week). Mechanical hyperalgesia was assessed using electronic von Frey testing after arthritis establishment at 24 h or 7 days following the third intra‐articular injection.
Ana Carolina de Figueiredo Costa, Luane Macedo de Sousa, Delane Viana Gondim   +2 more
wiley   +1 more source

Allogeneic mesenchymal stromal cells overexpressing mutant human Hypoxia-inducible factor 1-α (HIF1-α) in an ovine model of acute myocardial infarction [PDF]

, 2016
Background-Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors.
Crottogini, Alberto José, De Lorenzi, Andrea, Giménez, Carlos Sebastián, Hnatiuk, Anna, Jen, Cheng Hao, Laguens, Rubén, Lee, Won Hee, Locatelli, Paola, Olea, Fernanda Daniela, Ong, Sang-Ging, Riegler, Johannes, Wu, Joseph C.   +11 more
core   +1 more source

Soft‐Tissue Integration of Dental Implants: Formation, Maintenance, and Relevance for Peri‐Implant Health

Journal of Periodontal Research, EarlyView.
Sixty years after the introduction of dental implants, it is clear that soft‐tissue integration is as essential as osseointegration. This review outlines how peri‐implant soft tissues develop, protect, and sometimes fail, revealing key knowledge gaps and new opportunities to improve long‐term implant stability.
Fabiana Aellos, Axelle Clavelier, Bo Liu, Alison Wan, Giovanni E. Salvi, Mario Romandini, Jill A. Helms   +6 more
wiley   +1 more source