Results 91 to 100 of about 190,321 (310)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

On regular drawn symbolic picture languages

Information and Computation, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
COSTAGLIOLA, Gennaro, DEUFEMIA, Vincenzo, FERRUCCI, Filomena, GRAVINO, Carmine   +3 more
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A comparison of preschool children's discussions with parents during picture book and chapter book reading [PDF]

, 2014
Discussions that occur during book reading between parents and preschool children relate to children’s language development, especially discussions during picture books that include extended discourse, a form of abstract language.
Leech, Kathryn, Rowe, Meredith
core   +1 more source

Targeted language training combined with transcranial direct current therapy for Wernicke aphasia in the sequelae stage: A case report

Brain Disorders
Objective: To observe the effects of combining targeted language training with transcranial direct current stimulation (tDCS) on speech rehabilitation in senile stroke patients with Wernicke's aphasia in the sequelae stage.
Juan Yang, Huozhong Yuan
doaj   +1 more source

LANGUAGE AS PICTURE IN PLATO’S CRATYLUS AND WITTGENSTEIN’S TRACTATUS

Tópicos, 2013
The aim of the following article is to compare Plato and Wittgenstein’s doctrines of language as a picture, focusing on the Cratylus and the Tractatus Logico-Philosophicus.
Shlomy Mualem
doaj   +1 more source

Context-Sensitive String Languages and Recognizable Picture Languages

Information and Computation, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Michel Latteux, David Simplot
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

L’isomorfismo nel "Tractatus logico-philosophicus": il caso dell’identità

Philosophy Kitchen, 2017
The notion of isomorphism provides an important key to understand the picture theory of language, as given in Tractatus logico-philosophicus. This paper discusses the thesis of isomorphism between language and world, surveying a particular issue of ...
Ludovica Conti
doaj   +1 more source

Descriptive complexity for pictures languages

, 2012
This paper deals with logical characterizations of picture languages of any dimension by syntactical fragments of existential second-order logic. Two classical classes of picture languages are studied: - the class of recognizable picture languages, i.e.
Grandjean, Etienne, Olive, Frédéric
openaire   +5 more sources