Results 71 to 80 of about 5,617,278 (381)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ORAL PROFICIENCY IN PAKPAK LANGUAGE: AN ISSUE IN MAINTAINING PAKPAK LANGUAGE [PDF]

open access: yes, 2017
Students’ low proficiency speaking in their mother language has attracted the attention of previous researchers for decades. This study was conducted in one Primary School in Desa Bintang, Sidikalang, Dairi District, North Sumatera Province.
Murni , Sri Minda
core  

Dynamic reconfiguration of the language network preceding onset of speech in picture naming

open access: yesHuman Brain Mapping, 2014
Language production is a complex neural process that requires the interplay between multiple specialized cortical regions. We investigated modulations in large‐scale cortical networks underlying preparation for speech production by contrasting cortico ...
Mia Liljeström   +3 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Cognitive-discursive approach to the verb study [PDF]

open access: yesJužnoslovenski Filolog, 2006
Genetically substantives are primary in language, but diachronically verbs strengthen their position in language world picture. Synchronically verbs reflect relations between substances in language system and form these relations in discourse.
Čarikova O.N.
doaj   +1 more source

The names of the town and villages of Gozo (Malta) [PDF]

open access: yes, 2010
The Maltese islands have been dominated by various rulers who left an imprint on the life, customs, and language of the inhabitants. This is evident also in the toponymy of the archipelago.
Zammit Ciantar, Joe
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Global Education in Second Language Teaching [PDF]

open access: yes, 1999
This article paints an optimistic picture of the role we second language teachers can play not only in improving our students' language proficiency but also in infusing global education into our classes as we join with our students to address global ...
Cates, K. (Kip), Jacobs, G. M. (George)
core   +1 more source

Electromagnetic Form Factors and the Localization of Quark Orbital Angular Momentum in the Proton

open access: yes, 2002
A new picture is given of generalized parton distributions probed in experiments in which the probe scale $Q^{2}$ and the momentum transfer $\DD^{2}$ are well separated. Application of this picture to the $Q^{2}$ dependence of the form factors $F_{1}, F_{
Buniy, Roman V.   +2 more
core   +2 more sources

Reaching out to the other side: Formal-linguistics-based SLA and Socio-SLA [PDF]

open access: yes, 2013
Generative linguistics has long been concerned with the linguistic competence of the “ideal speaker-listener, in a completely homogeneous speech-community, who knows its language perfectly” (Chomsky 1965: 3).
Kinzler   +30 more
core   +2 more sources

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