Results 61 to 70 of about 4,512,323 (269)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
SPATIAL PARAMETRIZATION OF THE KAZAKH LANGUAGE PICTURE OF THE WORLD
Вестник Кемеровского государственного университета, 2013 This article examines the layered structure of the spatial picture of the world, reflected in the Kazakh language. The Kazakh language picture of the world represents the space as an infinite horizontal plane, conventionally denoted as «steppe».
A. Zh. Bahralinova
doaj
The concept jylme ‘language’ in the language and ordinary world views of Mari
Финно-угорский мир, 2018 The article describes the concept jylme ‘language’ in the Mari language. It considers the ways of representation of the concept in phraseology and in folklore texts, considering that the concept arises as a result of the interaction of national tradition
Liubov A. Abukaeva
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Brain DisordersObjective: To observe the effects of combining targeted language training with transcranial direct current stimulation (tDCS) on speech rehabilitation in senile stroke patients with Wernicke's aphasia in the sequelae stage.
Juan Yang, Huozhong Yuan
doaj +1 more source
LANGUAGE AS PICTURE IN PLATO’S CRATYLUS AND WITTGENSTEIN’S TRACTATUS
Tópicos, 2013 The aim of the following article is to compare Plato and Wittgenstein’s doctrines of language as a picture, focusing on the Cratylus and the Tractatus Logico-Philosophicus.
Shlomy Mualem
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source