Results 61 to 70 of about 4,493,322 (326)

Intersemiotische Kommunikation im frühen Fremdsprachenunterricht

open access: yesGlottodidactica, 2008
The article refers to the constitutive elements of intersemiotic communication in the didactics of foreign languages. It indicates, that you can communicate not only using verbal language, but nonverbal elements such as for example pictures or music ...
Gabriela Gorąca
doaj   +1 more source

Query Containment for Highly Expressive Datalog Fragments [PDF]

open access: yes, 2014
The containment problem of Datalog queries is well known to be undecidable. There are, however, several Datalog fragments for which containment is known to be decidable, most notably monadic Datalog and several "regular" query languages on graphs ...
Bourhis, Pierre   +2 more
core   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Le trilinguisme au Luxembourg

open access: yesLa Bretagne Linguistique, 1991
In this presentation, the focus will be on the use of languages in Luxembourg, where three languages are spoken: Lëtzebuergesch, German and French. Situated between Belgium, France and Germany, the country has an area of 2,587 km2 and had a population of
Fernande Krier
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Finitary languages

open access: yes, 2011
The class of omega-regular languages provides a robust specification language in verification. Every omega-regular condition can be decomposed into a safety part and a liveness part.
Chatterjee, Krishnendu   +1 more
core   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Misrepresentation of Chinese Culture in American Picture Books Through Written and Visual Languages

open access: yesVestnik za Tuje Jezike
Language is a communication system which consists of signs, symbols, gestures, and so on. In picture books, a special genre of children’s books, pictures can be regarded as a visual language because meaning can be conveyed from the authors to readers by
Wangbei Tu
doaj   +1 more source

Rural meets Urban: Advanced Placement Rural High School Students Supporting Urban Dual Language Learners [PDF]

open access: yes, 2017
High School Advanced Placement (AP) Spanish students from a rural school district in Upstate New York translated picture books for second grade students at Urban Primary, where Spanish is primarily spoken at home.
Schultz, Susan
core   +1 more source

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