Results 191 to 200 of about 31,142 (263)

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine is a potent regulator of neurotransmission and neuronal excitability, through activation of Gi coupled adenosine A1 receptors (A1Rs). Adenosine has gained interest as an anticonvulsant because of its endogenous involvement in ending seizure activity, but peripheral side effects require local application.
Erine Craey   +8 more
wiley   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot   +3 more
wiley   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Facilitated Transport of Organic Contaminants in a High Concentration, Multicomponent Plume

open access: yesGroundwater Monitoring &Remediation, EarlyView.
Abstract A field experiment evaluated the transport of organic contaminants in a plume from hazardous waste disposal areas at the Rocky Mountain Arsenal. The plume contained many xenobiotic contaminants, with widely varying expected mobilities.
D. M. Mackay   +7 more
wiley   +1 more source

Non‐native pink salmon Oncorhynchus gorbuscha carcasses benefit native benthic macroinvertebrates

open access: yesJournal of Fish Biology, EarlyView.
Abstract The invasion of the North Atlantic by pink salmon Oncorhynchus gorbuscha has raised concerns regarding their impact on coastal rivers. Although the influence of marine‐derived nutrients from returning adult O. gorbuscha on rivers in their native range has received much attention, the ecological consequences of invasive O.
Hui Wei   +9 more
wiley   +1 more source

Prehabilitation in Implant Dentistry: An Essential Strategy for Primordial Prevention of Peri‐Implant Diseases

open access: yesJournal of Periodontal Research, EarlyView.
Peri‐implant diseases (PIDs) are highly prevalent and threaten both the success and longevity of implant‐supported prostheses. Their prevention should begin before implant surgery (i.e., primordial prevention) by avoiding risk factor exposure and ensuring optimal implant placement conditions. Prehabilitation, a multimodal strategy already used in other
Maria Clotilde Carra, Philippe Bouchard
wiley   +1 more source

Sleep and Maladaptive Personality Traits: A Twin Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep is essential for human functioning, but little attention has been paid to the interplay between sleep and maladaptive personality traits. We examined genetic and environmental associations between sleep and four maladaptive domains (MDs)—Negative Affectivity, Detachment, Disinhibition, and Psychoticism—within the framework of the DSM‐5 ...
Ziyu Ren   +11 more
wiley   +1 more source

Agents' Behavior and Interest Rate Model Optimization in DeFi Lending

open access: yesMathematical Finance, EarlyView.
ABSTRACT Contrasting sharply with traditional money, bond, and bond futures markets, where interest rates emerge organically from participant interactions, DeFi lending platforms employ rule‐based interest rates that are algorithmically set. Thus, the selection of an effective interest rate model (IRM) is paramount for the success of a lending protocol.
Charles Bertucci   +4 more
wiley   +1 more source

Effects of Video‐Based Health Education on Birth Outcomes and Anaemia Status of Mothers in Dirashe District South Ethiopia: A Cluster Randomized Controlled Trial

open access: yesMaternal &Child Nutrition, EarlyView.
ABSTRACT Undernutrition and infections during pregnancy result in low birth weight (LBW) and maternal anaemia. Social behaviour change communication (SBCC) can promote recommended health practices, potentially improving maternal and neonatal outcomes.
Wanzahun Godana Boynito   +9 more
wiley   +1 more source

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