Results 141 to 150 of about 1,456,087 (324)

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu   +11 more
wiley   +1 more source

El pie valgo [PDF]

open access: yes, 2015
El pie valgo es aquel que cursa con la desviación del retropié en pronación. Se manifiesta por la pronación del retropié, la addución y la pronación de la articulación mediotarsiana, la supinación y la abducción del ...
Oller Asensio, Antonio
core  

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

open access: yesAdvanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma   +10 more
wiley   +1 more source

By pass distales al cuello de pie

open access: yesCirugía del Uruguay, 1997
Se analizan retrospectivamente los resultados de 48 puentes distales al cuello del pie realizados en 43 pacientes, 32 hombres y 11 mujeres, con una edad media de 70 años, en un período de 20 meses.
Carmelo Gastambide   +5 more
doaj  

Learning from a Piece of Pie: the Empirical Content of Nash Bargaining [PDF]

open access: yes
Consider a model of bargaining, in which two players, 1 and 2, share a pie of size y. The bargaining environment is described by a set of parameters ? that may affect agents' preferences over the agreement sharing, the status quo outcome, or both.
Olivier Donni, Pierre-André Chiappori
core  

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

open access: yesAdvanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou   +19 more
wiley   +1 more source

Luxación compleja de la articulación del Lisfranc y de Chopart

open access: yesCirugía del Uruguay, 2019
Presentado en sesión de 23  de octubre de ...
Gerardo Caprio
doaj  

Compromiso de las articulaciones vecinas en la evolución alejada de la artrodesis de tobillo

open access: yesRevista de la Asociación Argentina de Ortopedia y Traumatología
Introducción: La artrodesis tibioastragalina es una opción para tratar la artrosis de tobillo en pacientes que no responden a las medidas conservadoras.
Alberto Macklin Vadell   +7 more
doaj   +1 more source

Escaping RGBland: Selecting Colors for Statistical Graphics [PDF]

open access: yes, 2007
Statistical graphics are often augmented by the use of color coding information contained in some variable. When this involves the shading of areas (and not only points or lines) - e.g., as in bar plots, pie charts, mosaic displays or heatmaps - it is ...
Hornik, Kurt   +2 more
core  

Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems

open access: yesAdvanced Science, EarlyView.
Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li   +6 more
wiley   +1 more source

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