Results 131 to 140 of about 1,392,738 (297)
Advanced Science, EarlyView.G4‐binding proteins (G4BPs) that specifically co‐bind G4s in the presence of small‐molecule ligands represent a critical but unexplored class of proteins. We introduce G4‐Ligand‐Directed PROTACs (G4L‐TACs), a chemical platform that couples G4 ligands (PDS) to E3 recruiters to selectively degrade these ligand‐co‐binding G4BPs.
Mao‐Lin Li +8 more
wiley +1 more source
Braquimetatarsia: Revisión de la literatura a propósito de dos casos. Informe de casos
Salud UIS, 2015 La braquimetatarsia es una enfermedad en el pie, considerada rara, definida como el acortamiento anormal del metatarsiano. Su incidencia en la población está en el rango de 0.02- 0.05%, y predomina en el sexo femenino (25:1).
Diego F Rincón C +3 more
doaj
Advanced Science, EarlyView.Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Commitment in Alternating Offers Bargaining [PDF]
We extend the Ståhl-Rubinstein alternating-offer bargaining procedure to allow players, prior to each bargaining round, to simultaneously and visibly commit to some share of the pie.
Miettinen, Topi, Perea, Andrés
core
, 2011 [ES] Definición del término Pie en el diccionario Dicter. [EN] Definition of the word Pie in the dictionary Dicter.
openaire +1 more source
Advanced Science, EarlyView.TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source
Learning from a Piece of Pie: the Empirical Content of Nash Bargaining [PDF]
Consider a model of bargaining, in which two players, 1 and 2, share a pie of size y. The bargaining environment is described by a set of parameters ? that may affect agents' preferences over the agreement sharing, the status quo outcome, or both.
Olivier Donni, Pierre-André Chiappori
core
MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion
Advanced Science, EarlyView.ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong +9 more
wiley +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Heterointerface‑Enabled Electrocatalysis for Efficient Energy Conversion
Advanced Science, EarlyView.Functionally distinct A/B materials can be integrated at the nanoscale to create customized heterointerfaces with tunable band alignment and charge redistribution, providing fast electron and ion transport channels as well as cooperative dual active sites.
Liuru Fang +3 more
wiley +1 more source