Results 131 to 140 of about 241,000 (259)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Who Gets Grandma's Yellow Pie Plate? Video

, 1999
Runtime 12:30 minutesUniversity of Minnesota, Extension Service. (1999). Who Gets Grandma's Yellow Pie Plate? Video.
University of Minnesota, Extension Service
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The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source

Publication industrielle des machines outils et appareils : les plus perfectionnés et les plus récents employés dans les différentes branches de l'industrie française et étrnagère

, 1874
Na cub. do v.R\XXVR\: "Exposition universelle de 1878: Mécanique générale goupe Vi- Classe 54 Medaille d'or/Armengaud Ainé". Este tomo está falto da portNo T. III, V:Vingt. troisième: "Boulogne (Seine).- Imprimerie Jules Boyer"Marca tip.
Armengaud, Jacques-Eugène, 1810-1891
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Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

A Brochure & Pamphlet volume 2

, 1991
Dalam masyarakat yang makmur saat ini, peningkatan standar hidup telah disertai dengan permintaan dari konsumen akan produk dan layanan dengan kualitas yang lebih baik. Pada saat yang sama, kesadaran produsen akan presentasi lebih tinggi dari sebelumnya.
PIE Books
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Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Caso clínico: Pie doloroso poscirugía del mediopié

, 2012
Presentamos un caso de pie doloroso con deformidad postraumática fija y estructurada tras diversas cirugías a nivel de retropié con resultados insatisfactorios clínica y radiológicamente.
Fernández Torres, José Juan, Castillo Blanco, Gabriel del, Alegrete Parra, Andrés, Carranza Bencano, Andrés, Tejero García, Sergio   +4 more
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Relationship between normal mobility of the first ray of the foot and low back pain. Cross-sectional observational study

Introducción: El objetivo del estudio fue analizar si existe una diferencia en la movilidad del primer radio del pie entre personas con y sin dolor lumbar, y si dicha movilidad pudiera estar relacionada con la presencia de lumbalgia. Pacientes y métodos:
Granados-Gómez, Patricia, Reina Bueno, María, Gómez-Castro, Mercedes, Munuera Martínez, Pedro Vicente   +3 more
core   +1 more source